Department of Otolaryngology-Head & Neck Surgery, University of Cincinnati, College of Medicine, 3151 Bellevue Avenue, Cincinnati, OH 45219, USA.
Department of Otolaryngology-Head & Neck Surgery, University of Cincinnati, College of Medicine, 3151 Bellevue Avenue, Cincinnati, OH 45219, USA.
Surg Oncol Clin N Am. 2024 Oct;33(4):761-773. doi: 10.1016/j.soc.2024.04.009. Epub 2024 Jul 8.
Over the last 2 decades, the paradigm of laryngeal cancer management has pivoted toward preserving laryngeal function without sacrificing oncologic outcomes. Transoral laser microsurgery has diminished the role of open laryngeal surgery. For early-stage laryngeal cancer, the common primary modalities are endoscopic laryngeal surgery and narrow field radiation. Total laryngectomy followed by either radiation or chemoradiation is option for advanced laryngeal cancer. In experienced hands and following meticulous patient selection, supracricoid laryngectomy may serve as a viable alternative to total laryngectomy to preserve laryngeal function. Total laryngectomy is still the recommended treatment in those with airway compromise and/or laryngeal dysfunction.
在过去的 20 年中,喉癌的治疗模式已经从牺牲肿瘤治疗效果来保留喉功能转变为保护喉功能而不牺牲肿瘤治疗效果。经口激光微创手术减少了开放性喉手术的应用。对于早期喉癌,常见的主要治疗方式是内镜喉外科手术和窄野放疗。对于晚期喉癌,全喉切除术加放疗或放化疗是一种选择。在有经验的医生手中,并经过仔细的患者选择,环状软骨上喉切除术可以作为全喉切除术的一种可行替代方法,以保留喉功能。对于有气道阻塞和/或喉功能障碍的患者,全喉切除术仍然是推荐的治疗方法。