Department of Otolaryngology-Head and Neck Surgery, Icahn School of Medicine at Mount Sinai, One Gustave L. Levy Place, New York, NY 10029, USA.
Department of Otolaryngology-Head and Neck Surgery, The Ohio State University Wexner Medical Center, 915 Olentangy River Road, Columbus, OH 43212, USA.
Otolaryngol Clin North Am. 2025 Feb;58(1):89-98. doi: 10.1016/j.otc.2024.07.025. Epub 2024 Sep 6.
Petrous bone cholesteatoma, or cholesteatoma that extends beyond the middle ear and mastoid, represents a rare but destructive pathology. Diagnosis can be difficult before substantial morbidity is incurred, and patients can present with life-threatening complications. Determination of disease extent and the functional status of the facial nerve and cochleovestibular system are critical in surgical planning. Typically, surgery involves ablative procedures with the goal of complete disease resection given the low likelihood of preserved inner ear function. In experienced hands, disease control and facial nerve outcomes are favorable; however, disease recidivism is not uncommon and, thus, these patients require lifelong surveillance.
岩骨胆脂瘤，或扩展至中耳和乳突以外的胆脂瘤，代表一种罕见但具有破坏性的病理。在发生实质性发病率之前，诊断可能很困难，并且患者可能会出现危及生命的并发症。确定疾病范围以及面神经和耳蜗前庭系统的功能状态对于手术计划至关重要。通常，手术涉及消融程序，鉴于内耳功能保存的可能性较低，因此手术的目标是完全切除病变。在经验丰富的手中，疾病控制和面神经结果是有利的；然而，疾病复发并不罕见，因此这些患者需要终身监测。
