Department of Emergency Medicine, Brooke Army Medical Center, Fort Sam Houston, TX, USA.
Department of Emergency Medicine, UT Southwestern, Dallas, TX, USA.
Am J Emerg Med. 2024 Nov;85:90-97. doi: 10.1016/j.ajem.2024.09.005. Epub 2024 Sep 2.
Ectopic pregnancy is a serious condition that can have significant morbidity and mortality.
This review highlights the pearls and pitfalls of ectopic pregnancy, including presentation, diagnosis, and management in the emergency department (ED) based on current evidence.
Ectopic pregnancy is a pregnancy that implants outside the normal uterine cavity. It most commonly presents with vaginal bleeding, abdominal or pelvic pain, and amenorrhea. Risk factors for ectopic pregnancy include abnormalities of the fallopian tube, prior ectopic pregnancy, and age over 35 years, but a significant number of patients with confirmed ectopic pregnancy will not have an identifiable risk factor. In patients with suspected ectopic pregnancy, evaluation includes quantitative serum hCG, blood type, and ultrasound. Ultrasound is necessary regardless of the hCG level. If the patient is hemodynamically unstable, resuscitation with blood products and early consultation of obstetrics/gynecology is necessary. Patients with confirmed ectopic pregnancy but who are otherwise stable may be managed medically or surgically. If a yolk sac or fetal pole is not seen in the uterus on ultrasound, this is considered a pregnancy of unknown location (PUL), which may represent an early, failed, or ectopic pregnancy. Stable patients with a PUL who can reliably follow up are managed with close specialist follow up and repeat 48 h HCG level. These patients need to have an hCG level repeated every 48 h until diagnosed with a viable pregnancy, failed pregnancy, or ectopic pregnancy.
Knowledge of the latest advances in managing ectopic pregnancy will help clinicians more quickly and accurately diagnose patients presenting with this potentially fatal condition.
宫外孕是一种严重的疾病,可导致严重的发病率和死亡率。
本综述强调了宫外孕的要点和陷阱,包括根据现有证据在急诊科的表现、诊断和处理。
宫外孕是指着床于子宫腔外的妊娠。它最常表现为阴道出血、腹痛或盆腔痛和闭经。宫外孕的危险因素包括输卵管异常、既往宫外孕和年龄超过 35 岁,但相当数量的确诊宫外孕患者没有可识别的危险因素。对于疑似宫外孕的患者,评估包括定量血清 hCG、血型和超声。无论 hCG 水平如何,超声都是必要的。如果患者血流动力学不稳定,需要进行血液制品复苏和早期妇产科咨询。对于确诊宫外孕但其他方面稳定的患者,可以进行药物或手术治疗。如果在子宫内超声上看不到卵黄囊或胎体,这被认为是妊娠位置不明(PUL),可能代表早期、失败或宫外孕。对于超声上稳定且可以可靠随访的 PUL 患者,应密切专科随访并重复 48 小时 hCG 水平。这些患者需要每 48 小时重复一次 hCG 水平,直到诊断出活胎、死胎或宫外孕。
了解宫外孕管理方面的最新进展将帮助临床医生更快速、准确地诊断出患有这种潜在致命疾病的患者。