Ye Hai, Xu Yajing, Mi Rui, Liu Yumeng, Lyu Yungang, Wu Songxiong, Wu Guangyao
Radiology Department, Shenzhen University General Hospital and Shenzhen University Clinical Medical Academy, Shenzhen, China.
Radiology Department, Shenzhen University General Hospital and Shenzhen University Clinical Medical Academy, Shenzhen, China.
World Neurosurg. 2024 Nov;191:e547-e555. doi: 10.1016/j.wneu.2024.08.165. Epub 2024 Sep 6.
This study aimed to assess variances in paravertebral muscle structure in individuals with idiopathic scoliosis (IS) through imaging techniques.
A cohort of 112 patients diagnosed with IS and treated at our institution between January and December 2023 was included in the analysis. During the same period, 37 patients with secondary scoliosis (SS) were included as controls. Imaging data were used to measure the Cobb angle of the apical vertebrae in scoliosis patients, along with the area and fat infiltration of the paravertebral muscles on both sides. Finally, the cross-sectional area of the paravertebral muscles and the degree of fat infiltration were comparatively evaluated.
In patients with IS, the paravertebral muscles on the concave side of the main curve were significantly larger than those on the convex side (P < 0.05). The concave/convex muscle area ratio in IS patients showed a positive correlation with the Cobb angle and scoliosis duration (both P < 0.05). There was no significant difference in the muscle area ratio between patients with IS and those with SS (P > 0.05). In IS, the paravertebral muscles on the concave side of the main curve exhibited more fat infiltration than those on the convex side, with this fat infiltration positively correlating with body mass index, Cobb angle, age, and scoliosis duration. Similarly, the degree of fat infiltration in the paravertebral muscles on the concave side of SS was more than that observed on the convex side. Furthermore, the degree of fat infiltration in the paravertebral muscles associated with SS was more pronounced compared to that seen in IS (P < 0.05).
In IS patients, the paravertebral muscles on the concave side are more prominent and exhibit more fat infiltration compared to those on the convex side. This fat infiltration positively correlates with the Cobb angle, scoliosis duration, body mass index, and age, possibly indicating scoliosis progression.
本研究旨在通过成像技术评估特发性脊柱侧凸（IS）患者椎旁肌结构的差异。
分析纳入了2023年1月至12月在本机构诊断为IS并接受治疗的112例患者。同期，纳入37例继发性脊柱侧凸（SS）患者作为对照。成像数据用于测量脊柱侧凸患者顶椎的Cobb角，以及双侧椎旁肌的面积和脂肪浸润情况。最后，对椎旁肌的横截面积和脂肪浸润程度进行比较评估。
在IS患者中，主弯凹侧的椎旁肌明显大于凸侧（P < 0.05）。IS患者的凹/凸肌面积比与Cobb角和脊柱侧凸病程呈正相关（均P < 0.05）。IS患者与SS患者的肌面积比无显著差异（P > 0.05）。在IS中，主弯凹侧的椎旁肌比凸侧表现出更多的脂肪浸润，这种脂肪浸润与体重指数、Cobb角、年龄和脊柱侧凸病程呈正相关。同样，SS患者凹侧椎旁肌的脂肪浸润程度高于凸侧。此外，与IS相比，SS相关的椎旁肌脂肪浸润程度更明显（P < 0.05）。
在IS患者中，凹侧的椎旁肌比凸侧更突出，且脂肪浸润更多。这种脂肪浸润与Cobb角、脊柱侧凸病程、体重指数和年龄呈正相关，可能表明脊柱侧凸进展。
