School of Allied Health, Human Services and Sport, La Trobe University, Melbourne, Australia.
School of Allied Health, Human Services and Sport, La Trobe University, Melbourne, Australia.
Neuroscience. 2024 Nov 1;559:181-187. doi: 10.1016/j.neuroscience.2024.09.003. Epub 2024 Sep 7.
The purpose of this study was to investigate the association between cognitive impairments and traumatic upper limb injuries of the acute phase.
A cross-sectional observational study was conducted with three groups: a nerve-injury group, a without nerve injury group, and a control group (uninjured participants). Demographic characteristics (e.g. age, sex, body mass index, and education) and traumatic characteristics (duration since injury, injury side, pain, light touch sensation, hand motor function) were recorded. Short-term memory and executive functions were assessed using Rey Auditory and Verbal Learning Test (RAVLT) and Stroop Color and Word Test (SCWT, including SIECT and SIECN), respectively.
The study comprised 43 participants in the nerve-injury group, 30 participants in the group without nerve injury, and 104 participants in the control group. Generalized linear model was applied to explore the difference of cognitive functions among three groups with impactors. Significantly poorer performance on the RAVLT was observed in the nerve-injury group compared to the other two groups, and lower score of SIECT in nerve-injury group was lower compared to the control group. However, there was no significant difference of SIECN among three groups. In addition, traumatic characteristics did not significantly impact RAVLT and SIECT (p > 0.05) in all injured participants.
Traumatic nerve injury to the upper limb appears to be associated with both short-term memory and executive function impairment, whereas musculoskeletal injuries without nerve damage showed no cognitive impairment. Therefore, it is important to monitor cognitive function following upper limb nerve injuries.
本研究旨在探讨急性上肢创伤与认知障碍之间的关系。
本研究为横断面观察性研究，纳入三组：神经损伤组、无神经损伤组和对照组（未受伤参与者）。记录人口统计学特征（如年龄、性别、体重指数和教育程度）和创伤特征（受伤时间、受伤侧、疼痛、轻触觉、手部运动功能）。使用 Rey 听觉和言语学习测试（RAVLT）和 Stroop 颜色和文字测试（SCWT，包括 SIECT 和 SIECN）分别评估短期记忆和执行功能。
研究纳入神经损伤组 43 例、无神经损伤组 30 例和对照组 104 例。广义线性模型用于探索三组间有冲击器的认知功能差异。与其他两组相比，神经损伤组的 RAVLT 表现明显较差，神经损伤组的 SIECT 评分也低于对照组。然而，三组间 SIECN 无显著差异。此外，创伤特征在所有受伤参与者中均未显著影响 RAVLT 和 SIECT（p>0.05）。
上肢创伤性神经损伤似乎与短期记忆和执行功能障碍有关，而无神经损伤的肌肉骨骼损伤则无认知障碍。因此，监测上肢神经损伤后的认知功能很重要。
