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肾移植受者中的李斯特菌病。10例(作者译)

[Listeriosis in the kidney transplant recipients. Ten cases (author's transl)].

作者信息

Buset M, Dupont E, Vereerstraeten P, Kinnaert P, Yourassowsky E, Van Geertruyden J, Toussaint C

出版信息

Nouv Presse Med. 1979 Oct 22;8(40):3231-4.

PMID:392456
Abstract

Three clinical pictures were found in ten cases of listeriosis after renal transplantation: septicemia (six cases), meningo-encephalitis (three cases) and asymtomatic but recurrent bacteriuria (one case). Several features demonstrate profound immunologic disturbances in the recipient: close relationship in 9 cases out of 10 between infection and high doses of immunosuppressive drugs, unfavorable outcome of graft (accelerated rejection in 4 cases out of 10) and association in one case with lethal pulmonary infection due to opportunistic agents (cytomegalovirus and Pneumocystis carinii).

摘要

肾移植后10例李斯特菌病患者出现了三种临床表现:败血症(6例)、脑膜脑炎(3例)和无症状但反复发作的菌尿症(1例)。有几个特征表明受者存在严重的免疫紊乱:10例中有9例感染与高剂量免疫抑制药物密切相关,移植肾预后不良(10例中有4例加速排斥反应),1例与机会性病原体(巨细胞病毒和卡氏肺孢子虫)引起的致命肺部感染有关。

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