Nona S N, Trowell S C, Cronly-Dillon J R
FEBS Lett. 1985 Jul 1;186(1):111-5. doi: 10.1016/0014-5793(85)81350-8.
The concept of critical period plasticity in rat visual cortex has been studied in terms of changes in the level of filamentous actin and of the 200 kDa neurofilament polypeptide. Our results suggest that the postnatal developmental profile of filamentous actin is affected by visual experience, as a consequence of eye-opening. No such correlation, however, is detected for the 200 kDa neurofilament polypeptide. The significance of these findings in relationship to neuronal plasticity is discussed in terms of changes in the state and equilibrium conditions of the cytoskeletal proteins.
大鼠视觉皮层关键期可塑性的概念已根据丝状肌动蛋白水平和200 kDa神经丝多肽的变化进行了研究。我们的结果表明，丝状肌动蛋白的出生后发育概况受视觉经验的影响，这是睁眼的结果。然而，未检测到200 kDa神经丝多肽存在这种相关性。根据细胞骨架蛋白的状态和平衡条件的变化，讨论了这些发现与神经元可塑性相关的意义。
