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一例腰椎孤立性纤维瘤或血管外皮细胞瘤。

A case of lumbar spinal solitary fibrous tumor or hemangiopericytomas.

作者信息

Alkulli Osama A, Albaradie Omar Abdulrahman, Alghamdi Khalid Talal, Kutub Layan Hussam, Kutub Hussam

机构信息

College of Medicine, King Saud bin Abdulaziz University for Health Sciences, King Abdulaziz Medical City, National Guard Health Affairs, Jeddah, Saudi Arabia.

Department of Neurosurgery, King Faisal Specialist Hospital and Research Centre, Riyadh, Saudi Arabia.

出版信息

Surg Neurol Int. 2024 Aug 23;15:301. doi: 10.25259/SNI_538_2024. eCollection 2024.

DOI:10.25259/SNI_538_2024
PMID:39246775
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11380903/
Abstract

BACKGROUND

Solitary fibrous tumors (SFTs) account for 3.7% of all soft-tissue sarcomas, with an annual incidence of 0.35/100,000 individuals. Notably, although 20% involve the central nervous system, only one in 10 occurs in the spine versus the brain.

CASE DESCRIPTION

A 46-year-old female presented with 18 months of left lower extremity sciatica. On examination, she had a 60° limitation of straight leg raising but was otherwise neurologically intact. The lumbar magnetic resonance revealed a dumbbell tumor at the L4-L5 level filing the canal, causing cauda equina compression and extending into the left L45 foramen. The patient successfully underwent a L4 left hemi-laminectomy for tumor resection. The postoperative World Health Organization (WHO) histopathology was consistent with a SFT/WHO Grade I hemangiopericytoma (HPC).

CONCLUSION

A 46-year-old female with a lumbar L4 SFT with the left L45 foraminal extension successfully underwent a left hemilaminectomy for GTR of an SFT/WHO Grade I HPC.

摘要

背景

孤立性纤维瘤(SFTs)占所有软组织肉瘤的3.7%,年发病率为0.35/10万。值得注意的是,尽管20%累及中枢神经系统,但发生在脊柱的仅占十分之一,而发生在脑部的占十分之九。

病例描述

一名46岁女性出现18个月的左下肢坐骨神经痛。检查时,她直腿抬高受限60°,但其他神经系统检查正常。腰椎磁共振成像显示L4-L5水平有一个哑铃形肿瘤占据椎管,导致马尾神经受压,并延伸至左侧L45椎间孔。患者成功接受了L4左侧半椎板切除术以切除肿瘤。术后世界卫生组织(WHO)组织病理学检查结果与SFT/WHO I级血管外皮细胞瘤(HPC)一致。

结论

一名46岁女性患有腰椎L4 SFT并延伸至左侧L45椎间孔,成功接受了左侧半椎板切除术,以实现SFT/WHO I级HPC的根治性肿瘤切除(GTR)。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/48ad/11380903/59b5bf785539/SNI-15-301-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/48ad/11380903/8fbf33012e17/SNI-15-301-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/48ad/11380903/59b5bf785539/SNI-15-301-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/48ad/11380903/8fbf33012e17/SNI-15-301-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/48ad/11380903/59b5bf785539/SNI-15-301-g002.jpg

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本文引用的文献

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Spinal Solitary Fibrous Tumors: An Original Multicenter Series and Systematic Review of Presentation, Management, and Prognosis.脊柱孤立性纤维瘤:一项原始多中心研究及关于临床表现、治疗与预后的系统评价
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Novel Therapeutic Options for Solitary Fibrous Tumor: Antiangiogenic Therapy and Beyond.孤立性纤维性肿瘤的新型治疗选择:抗血管生成治疗及其他。
Cancers (Basel). 2022 Feb 20;14(4):1064. doi: 10.3390/cancers14041064.
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Nationwide incidence of sarcomas and connective tissue tumors of intermediate malignancy over four years using an expert pathology review network.
利用专家病理审查网络,四年间全国范围内的中间恶性肉瘤和结缔组织肿瘤的发病率。
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