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与乳腺癌晚期诊断和治疗开始相关的因素。

Factors linked to the late diagnosis of breast cancer and the initiation of treatment.

机构信息

Department of Medical Oncology, Mohammed VI University Hospital, University of Cady Ayyad, Marrakech, Morocco.

Department of Onco Radiotherapy, Orleans University Hospital, Orleans, France.

出版信息

Pan Afr Med J. 2024 Apr 24;47:207. doi: 10.11604/pamj.2024.47.207.42734. eCollection 2024.

DOI:10.11604/pamj.2024.47.207.42734
PMID:39247784
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11380621/
Abstract

Breast cancer is the first cancer in women in terms of incidence and mortality. In Morocco, it is a public health problem. Its prognosis is strongly linked to the stage at which it is diagnosed. It is a pathology for which diagnosis means are highly developed today, ranging from early detection to the demonstration of infra-clinical lesions, which has markedly improved the prognosis in developed countries. This work aims to identify the factors that lead patients to consult at an advanced stage in our daily practice. It is a retrospective study carried out from January 2018 to December 2018 including 525 patients with breast cancer followed in the medical oncology department of the Mohammed VI University Hospital in Marrakech. The average age was 54. The average time for consultation was 10.3 months. 63% of patients were from rural areas. Delayed diagnosis affected women above 35 years of age (80%). The most common method of detection was self-examination in 74% of cases. Inflammation (2.66%), ulceration (1.14%), signs of metastases (17.14%), and isolated breast nodes (79.4%) were other reasons for consultation. 82.2% of patients were locally advanced at the time of diagnosis. The time for treatment in our study was 3.7 weeks. In our practice, it is the conjunction of ignorance, poverty, socio-cultural habits, and difficult geographical access that are the essential factors in the late diagnosis of breast cancer.

摘要

乳腺癌是女性中发病率和死亡率最高的癌症。在摩洛哥,它是一个公共卫生问题。其预后与诊断时的阶段密切相关。这是一种诊断手段非常发达的病理学,从早期检测到亚临床病变的证明,这在发达国家显著改善了预后。这项工作旨在确定导致患者在我们的日常实践中就诊晚期的因素。这是一项回顾性研究,于 2018 年 1 月至 2018 年 12 月进行,包括在马拉喀什穆罕默德六世大学医院肿瘤内科就诊的 525 名乳腺癌患者。平均年龄为 54 岁。平均就诊时间为 10.3 个月。63%的患者来自农村地区。延迟诊断影响 35 岁以上的女性(80%)。最常见的发现方法是自我检查,占 74%。炎症(2.66%)、溃疡(1.14%)、转移迹象(17.14%)和孤立的乳房淋巴结(79.4%)是其他就诊原因。82.2%的患者在诊断时处于局部晚期。在我们的研究中,治疗时间为 3.7 周。在我们的实践中,导致乳腺癌晚期诊断的主要因素是无知、贫困、社会文化习惯和难以获得地理通道。

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本文引用的文献

1
[Study of breast cancer treatment waiting times in Sousse, Tunisia].[突尼斯苏塞乳腺癌治疗等待时间的研究]
Sante Publique. 2016 May-Jun;28(3):331-40.
2
Diagnosis delay in Libyan female breast cancer.利比亚女性乳腺癌的诊断延误
BMC Res Notes. 2012 Aug 21;5:452. doi: 10.1186/1756-0500-5-452.
3
A meta-analysis of male breast cancer in Africa.非洲男性乳腺癌的荟萃分析。
Breast. 2012 Jun;21(3):237-41. doi: 10.1016/j.breast.2012.01.004. Epub 2012 Feb 1.
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Cancer care challenges in developing countries.发展中国家的癌症护理挑战。
Cancer. 2012 Jul 15;118(14):3627-35. doi: 10.1002/cncr.26681. Epub 2011 Dec 16.
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Diagnosis delay of breast cancer and its associated factors in Malaysian women.马来西亚女性乳腺癌的诊断延误及其相关因素。
BMC Cancer. 2011 Apr 17;11:141. doi: 10.1186/1471-2407-11-141.
6
Perceptions of breast cancer across the lifespan.对乳腺癌在整个生命周期中的认知。
J Psychosom Res. 2003 Feb;54(2):141-6. doi: 10.1016/s0022-3999(02)00522-6.