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85 岁以上老年男性高血压患者 24 小时动态血压监测的特点:一项观察性研究。

Characteristics of 24-h ambulatory blood pressure monitoring in elderly hypertensive males: An observational study of 85 year older patients.

机构信息

Department of Cardiology, West China Hospital, Sichuan University, Chengdu, China.

Department of Geriatric Medicine, General Hospital of Western Theater Command of PLA, Chengdu, Sichuan, China.

出版信息

J Clin Hypertens (Greenwich). 2024 Nov;26(11):1237-1245. doi: 10.1111/jch.14897. Epub 2024 Sep 9.

Abstract

Although hypertension is highly prevalent among the elderly and significantly contributes to cardiovascular disease risk, studies focusing on male elderly individuals over 85 years old are relatively scarce. This study aimed to investigate ambulatory blood pressure monitoring (ABPM) characteristics in male hypertensive patients aged over 85 years. These included demographic characteristics, antihypertensive drug use, 24-h ABPM values, diabetes, coronary heart disease, sleep disorders, smoking history, and drinking history, and the differences in ABPM between the age groups over and under 85 years old were analyzed. A total of 585 elderly hypertensive patients were included. The mean systolic blood pressure in individuals aged over 85 years was significantly greater throughout the day (131.57 ± 12.52 mmHg vs. 123.75 ± 2.74 mmHg, p < .001). In the 85 years older age group, the nighttime variability coefficient of SBP was lower at 7.84 ± 2.9 than the under 85 years age group 8.92 ± 3.13 (p < .001). The 85 years older age group age group presented a significantly greater whole-day systolic blood pressure standard deviation of ABPM (13.2 ± 3.19 vs. 12.47 ± 3.05, p = .005) compared with those under the age of 85 years. In the 85 years older age group, the proportion of individuals with the reverse dipper pattern was higher (48.15% vs. 38.31%, p = .017) than under 85 years age group. This study revealed that elderly male hypertensive patients aged over 85 years presented elevated average blood pressure levels. The research investigated ABPM characteristics. Older hypertensive individuals are more likely to have a reverse-dipper blood pressure pattern.

摘要

虽然高血压在老年人中患病率很高,并且对心血管疾病风险有重要影响,但针对 85 岁以上男性老年人的研究相对较少。本研究旨在探讨 85 岁以上男性高血压患者的动态血压监测(ABPM)特征。这些特征包括人口统计学特征、降压药物使用情况、24 小时 ABPM 值、糖尿病、冠心病、睡眠障碍、吸烟史和饮酒史,并分析了 85 岁以上和 85 岁以下年龄组之间的 ABPM 差异。共纳入 585 例老年高血压患者。85 岁以上患者的日间平均收缩压明显更高(131.57 ± 12.52 mmHg 比 123.75 ± 2.74 mmHg,p < 0.001)。在 85 岁以上年龄组中,SBP 的夜间变异性系数为 7.84 ± 2.9,低于 85 岁以下年龄组的 8.92 ± 3.13(p < 0.001)。85 岁以上年龄组的 ABPM 全天收缩压标准差明显大于 85 岁以下年龄组(13.2 ± 3.19 比 12.47 ± 3.05,p = 0.005)。在 85 岁以上年龄组中,反向杓型血压模式的比例较高(48.15% 比 38.31%,p = 0.017)。本研究表明,85 岁以上男性老年高血压患者的平均血压水平升高。研究调查了 ABPM 特征。年龄较大的高血压患者更有可能出现反向杓型血压模式。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ef0c/11555539/8feb9d225f3b/JCH-26-1237-g004.jpg

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