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质量重于数量——重新思考社会参与在痴呆症预防中的作用:来自AgeWell.de试验的结果。

Quality over quantity - rethinking social participation in dementia prevention: results from the AgeWell.de trial.

作者信息

Kosilek Robert P, Wendel Flora, Zöllinger Isabel, Knecht Hanna Lea, Blotenberg Iris, Weise Solveig, Fankhänel Thomas, Döhring Juliane, Williamson Martin, Luppa Melanie, Zülke Andrea E, Brettschneider Christian, Wiese Birgitt, Hoffmann Wolfgang, Frese Thomas, König Hans-Helmut, Kaduszkiewicz Hanna, Thyrian Jochen René, Riedel-Heller Steffi G, Gensichen Jochen

机构信息

Institute of General Practice and Family Medicine, University Hospital, LMU Munich, Munich, Germany.

Institute and Clinic for Occupational, Social and Environmental Medicine, University Hospital, LMU Munich, Munich, Germany.

出版信息

Soc Psychiatry Psychiatr Epidemiol. 2024 Sep 9. doi: 10.1007/s00127-024-02757-4.

Abstract

BACKGROUND

Social participation as a protective factor against cognitive decline was one of the targets in the AgeWell.de study, a multi-domain interventional trial in a sample of older adults at increased risk for dementia. This study aimed to examine differential effects of the intervention and other influencing factors on social participation throughout the trial.

METHODS

A longitudinal analysis of study data at the primary follow-up after 24 months (n = 819) was conducted. The Lubben Social Network Scale (LSNS-6) was used to assess quantitative aspects of social networks, and self-reported social activities were classified using a three-tiered categorical framework to capture qualitative aspects.

RESULTS

A positive effect of the intervention was observed at the qualitative framework level, with an OR of 1.38 [95% CI: 1.05-1.82] for achieving or maintaining higher social participation at follow-up, while no effect could be detected on quantitative social network characteristics. Later phases of the Covid-19 pandemic showed a negative impact on the level of social participation at follow-up with an OR of 0.84 [95% CI: 0.75-0.95].

CONCLUSIONS

These findings suggest that by focusing on qualitative aspects of social participation as a component of dementia prevention, future interventions can promote enriched social interactions within established social networks.

TRIAL REGISTRATION

German Clinical Trials Register (DRKS) ID DRKS00013555.

摘要

背景

社会参与作为预防认知衰退的保护因素,是AgeWell.de研究的目标之一,该研究是一项针对痴呆症风险增加的老年人样本的多领域干预试验。本研究旨在探讨整个试验过程中干预措施和其他影响因素对社会参与的不同影响。

方法

对24个月主要随访时的研究数据(n = 819)进行纵向分析。使用鲁本社交网络量表(LSNS-6)评估社交网络的定量方面,并使用三层分类框架对自我报告的社交活动进行分类,以获取定性方面的信息。

结果

在定性框架层面观察到干预措施有积极效果,随访时实现或维持更高社会参与度的比值比为1.38 [95%置信区间:1.05 - 1.82],而在社交网络的定量特征方面未检测到效果。新冠疫情后期对随访时的社会参与水平有负面影响,比值比为0.84 [95%置信区间:0.75 - 0.95]。

结论

这些发现表明,通过将社会参与的定性方面作为痴呆症预防的一个组成部分加以关注,未来的干预措施可以促进既定社交网络内丰富的社会互动。

试验注册

德国临床试验注册中心(DRKS)标识符DRKS00013555。

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