>From the Liver Transplantation Center, Koç University Hospital, İstanbul, Turkey; and the Department of General Surgery, Başkent University School of Medicine, Ankara, Turkey.
Exp Clin Transplant. 2024 Aug;22(8):629-635. doi: 10.6002/ect.2023.0241.
Donor hepatectomy is a major surgery with a relatively safeprofile anda reportedcomplication rate of ~20%. Most complications are non-life threatening and are resolved with conservative measures. However, rare complications may need invasive precautions, ranging from percutaneous interventions to surgeries.
We retrospectively analyzed all living donor hepatectomies at our center. Donors were divided into 2 groups: laparoscopic and open procedures. We collected preoperative, intraoperative and postoperative data of donors.Donor complications were recorded separately intraoperatively and postoperatively according to the Clavien-Dindo postoperative complication classification system.
Between July 2018 and April 2023, 215 living donors had hepatectomies, including 48 laparoscopic and 167 open donor hepatectomies. Among donors, 91 were female donors (42.3%) and 124 were male donors (57.7%).The meanage of alldonorswas 33.5±8.1 years, and the mean body mass index (in kilogram divided by meters squared) was 24.6 ± 3.8. Among donors, 124 underwent right and 91 underwent left or left lateral hepatectomies. The mean operative time for all donors was 301 ± 83 minutes, the mean hospital stay was 5.8 ± 1.4 days, and the mean follow-up was 31.9 ± 15.8 months. Four patients (1.8%) had intraoperative complications, including 2 cases of bleeding, 1 diaphragm perforation, and 1 portal vein stenosis. Fourteen patients (7.4%) had major postoperative complications, with 5 patients requiring surgical intervention.
Donor hepatectomy is a complicated surgery that requires extensive preoperative preparation and appropriate donor selection. Postoperative donor complications can be diagnosed early with close follow-up, and a multidisciplinary approach is essential for complication management.
供体肝切除术是一种主要的手术，具有相对安全的特点，报告的并发症发生率约为 20%。大多数并发症没有生命危险，可以通过保守治疗解决。然而，罕见的并发症可能需要侵入性预防措施，范围从经皮介入到手术。
我们回顾性分析了我们中心所有的活体供肝切除术。供体分为两组：腹腔镜和开放性手术。我们收集了供体的术前、术中及术后数据。根据 Clavien-Dindo 术后并发症分类系统，术中及术后分别记录供体并发症。
2018 年 7 月至 2023 年 4 月，共有 215 例活体供体行肝切除术，其中腹腔镜 48 例，开放性 167 例。供体中，女性 91 例（42.3%），男性 124 例（57.7%）。所有供体的平均年龄为 33.5±8.1 岁，平均体重指数（千克除以米的平方）为 24.6 ± 3.8。供体中，124 例行右半肝切除术，91 例行左或左外侧半肝切除术。所有供体的平均手术时间为 301±83 分钟，平均住院时间为 5.8±1.4 天，平均随访时间为 31.9±15.8 个月。4 例（1.8%）供体发生术中并发症，包括 2 例出血，1 例膈穿孔，1 例门静脉狭窄。14 例（7.4%）供体发生严重术后并发症，其中 5 例需要手术干预。
供体肝切除术是一种复杂的手术，需要进行广泛的术前准备和适当的供体选择。术后供体并发症可以通过密切随访早期诊断，多学科方法对于并发症的管理至关重要。
