Dermatology, Barnsley Hospital NHS Foundation Trust, Barnsley, UK
School of Medicine and Population Health, The University of Sheffield Medical School, Sheffield, UK.
BMJ Case Rep. 2024 Sep 10;17(9):e259358. doi: 10.1136/bcr-2023-259358.
Herpes zoster (HZ), commonly known as shingles, is a painful blistering rash in dermatomal distribution, caused by the reactivation of varicella-zoster virus (VZV) that was acquired during a primary varicella infection. While commonly afflicting adults, cases of HZ in paediatric patients are infrequently reported. Such cases are predominantly reported in children who have had prior exposure to VZV, either during pregnancy, early childhood or have been vaccinated with live attenuated VZV. This report presents the first known case to our knowledge of HZ as the initial manifestation of a VZV infection in an immunocompetent toddler in the UK. The report details the chronology of the infection event and discusses the clinical context behind HZ presentations in paediatrics globally. It provides a compelling illustration of the uncommon presentation of VZV infection in an immunocompetent child devoid of antecedent virus exposure, thus meriting acknowledgement and potentially further investigation as to the cause.
带状疱疹（HZ），俗称带状疱疹，是一种疼痛性水疱性皮疹，呈皮节分布，由水痘-带状疱疹病毒（VZV）在原发性水痘感染期间被激活引起。HZ 通常影响成年人，但儿童病例罕见。此类病例主要发生在先前接触过 VZV 的儿童中，要么在怀孕期间、幼儿期或接种过减毒活 VZV 疫苗。本报告介绍了首例已知的 HZ 病例，该病例为英国一名免疫功能正常的幼儿 VZV 感染的初始表现。该报告详细描述了感染事件的时间顺序，并讨论了全球儿科 HZ 表现的临床背景。它有力地说明了免疫功能正常的儿童在没有先前病毒暴露的情况下 VZV 感染的罕见表现，因此值得承认，并可能进一步调查其原因。
