另一种与毛细胞白血病相关的免疫介导疾病：慢性活动性肝炎。

Another immune-mediated disease associated with hairy cell leukemia: chronic active hepatitis.

作者信息

Begley C G, Mackay I R, Bhathal P S

出版信息

Acta Haematol. 1985;73(2):104-5. doi: 10.1159/000206291.

DOI:10.1159/000206291

Abstract

This report describes a case of hairy cell leukemia (HCL) occurring with autoimmune chronic active hepatitis (CAH). A 74-year-old woman presented with typical clinical and histologic features of HCL for which splenectomy was performed. 2 years later she developed abnormal liver function tests due to auto-immune CAH. The liver function tests improved promptly after prednisolone therapy. HCL has been reported to occur with several immune-mediated diseases including polyarteritis nodosa, rheumatoid arthritis, hemolytic anemia, cutaneous vasculitis and monoclonal gammopathy with amyloidosis. This report adds a further example of HCL coexisting with an immune-mediated disease, in this case autoimmune CAH.

摘要

本报告描述了一例毛细胞白血病（HCL）合并自身免疫性慢性活动性肝炎（CAH）的病例。一名74岁女性表现出HCL典型的临床和组织学特征，为此进行了脾切除术。两年后，她因自身免疫性CAH出现肝功能检查异常。泼尼松龙治疗后肝功能检查迅速改善。据报道，HCL可与多种免疫介导的疾病同时发生，包括结节性多动脉炎、类风湿关节炎、溶血性贫血、皮肤血管炎和伴有淀粉样变性的单克隆丙种球蛋白病。本报告进一步提供了HCL与免疫介导疾病（本例为自身免疫性CAH）共存的实例。