肾衰竭患者尿液中的二胺氧化酶含量。
Diamine oxidase content in urine of patients with renal failure.
作者信息
Giarnieri D, Costa M T, Giarnieri V, Mondovi B
出版信息
Agents Actions. 1985 Apr;16(3-4):249-51. doi: 10.1007/BF01983152.
PMID:3925735
Abstract
Diamine oxidase activity was determined in twenty-seven samples collected from normal subjects and from patients with renal failure. The enzyme activity was absent or very low in the urine samples of normal subjects. The highest diamine oxidase activity was found in the patients affected with nephrosis, the Fanconi syndrome and renal transplantation, showing a relationship between urinary enzymatic activity and tubular damage, in accordance with the localization in the convoluted tubules.
摘要
在从正常受试者和肾衰竭患者收集的27个样本中测定了二胺氧化酶活性。正常受试者的尿液样本中酶活性缺失或非常低。在患有肾病、范科尼综合征和肾移植的患者中发现了最高的二胺氧化酶活性，这表明尿酶活性与肾小管损伤之间存在关联，这与该酶在曲小管中的定位一致。
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