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耐心等待,小心被咬:宾夕法尼亚州一例响尾蛇咬伤中毒病例

Bide Your Time With Bites: A Case of Rattlesnake Envenomation in Pennsylvania.

作者信息

Zonna Xavier, Banta Conor W, Lott Ronald, Shah Shweta, Battista Anthony, Colleran Caroline

机构信息

Internal Medicine, University at Buffalo, Buffalo, USA.

Internal Medicine, Geisinger Commonwealth School of Medicine, Scranton, USA.

出版信息

Cureus. 2024 Aug 9;16(8):e66539. doi: 10.7759/cureus.66539. eCollection 2024 Aug.

DOI:10.7759/cureus.66539
PMID:39258069
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11383865/
Abstract

This case report represents a 26-year-old male with no significant past medical history who presented to the emergency department in western Pennsylvania following a western diamondback rattlesnake () bite to his hand. His initial swelling was mild, and his coagulation studies were unremarkable, with minimal changes on repeat studies, and poison control recommended against antivenom administration. He was discharged home with oral antibiotics and analgesics due to his stable clinical course. However, he returned to the emergency department about 12 hours later with worsening pain and swelling that extended to his elbow. He was then given antivenom and transferred to a larger center for higher-level care, ultimately having symptom resolution after further antivenom administration. This report serves to underline the importance of clinician education regarding envenomation management throughout the United States, including areas without indigenous venomous snakes.

摘要

本病例报告介绍了一名26岁男性,既往无重大病史,在宾夕法尼亚州西部手部被西部菱斑响尾蛇()咬伤后前往急诊科就诊。他最初肿胀较轻,凝血检查无异常,复查时变化极小,毒物控制中心建议不给予抗蛇毒血清治疗。由于其临床过程稳定,他口服抗生素和镇痛药后出院回家。然而,约12小时后他因疼痛和肿胀加剧返回急诊科,肿胀已蔓延至肘部。随后他接受了抗蛇毒血清治疗,并被转至更大的中心接受更高级别的护理,在进一步给予抗蛇毒血清后最终症状得到缓解。本报告旨在强调在美国各地,包括没有本土毒蛇的地区,临床医生接受关于蛇咬伤处理教育的重要性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b967/11383865/03690c41e72d/cureus-0016-00000066539-i04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b967/11383865/a509717e3117/cureus-0016-00000066539-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b967/11383865/acce7366ad72/cureus-0016-00000066539-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b967/11383865/44f23a954f48/cureus-0016-00000066539-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b967/11383865/03690c41e72d/cureus-0016-00000066539-i04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b967/11383865/a509717e3117/cureus-0016-00000066539-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b967/11383865/acce7366ad72/cureus-0016-00000066539-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b967/11383865/44f23a954f48/cureus-0016-00000066539-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b967/11383865/03690c41e72d/cureus-0016-00000066539-i04.jpg

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本文引用的文献

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Toxins (Basel). 2024 Jan 11;16(1):37. doi: 10.3390/toxins16010037.
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The Effectiveness of Antibiotics in Managing Bacterial Infections on Bite Sites following Snakebite Envenomation.抗生素在处理蛇咬伤后咬伤部位细菌感染中的有效性。
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Fashionably late: A characterization of late coagulopathies in rattlesnake envenomations between Fab and F(ab')2 antivenoms.
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Venom composition of adult Western Diamondback Rattlesnakes (Crotalus atrox) maintained under controlled diet and environmental conditions shows only minor changes.在受控饮食和环境条件下饲养的成年西部菱斑响尾蛇(Crotalus atrox)的毒液成分仅显示出微小的变化。
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Snake Venom PLA, a Promising Target for Broad-Spectrum Antivenom Drug Development.蛇毒 PLA,广谱抗蛇毒药物研发的有前途的靶标。
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