Department of Nephrology, Changhai Hospital, Naval Medical University (Second Military Medical University), Shanghai, China.
Department of Nephrology, PLA Navy No. 905 Hospital, Naval Medical University (Second Military Medical University), Shanghai, China.
Ren Fail. 2024 Dec;46(2):2398188. doi: 10.1080/0886022X.2024.2398188. Epub 2024 Sep 11.
Diabetic nephropathy, as a severe microvascular complication of diabetes, manifests in four clinical types: classic, albuminuria regression, a rapid decline in kidney function (RDKF), and non-proteinuric or non-albuminuric DKD. Rapidly progressive diabetic nephropathy advances to end-stage renal disease more swiftly than the typical form, posing significant risks. However, a comprehensive understanding of rapidly progressive diabetic nephropathy is currently lacking. This article reviewed latest developments in genetic and clinical risk factors associated with rapidly progressive diabetic nephropathy, aiming to broad perspectives concerning the diagnosis and interventions of this condition.
糖尿病肾病是糖尿病严重的微血管并发症，表现为四种临床类型：经典型、白蛋白尿消退型、肾功能快速下降型（RDKF）和非蛋白尿或非白蛋白尿型 DKD。快速进展性糖尿病肾病比典型形式更快地进展为终末期肾病，带来重大风险。然而，目前对快速进展性糖尿病肾病的认识还不够全面。本文综述了与快速进展性糖尿病肾病相关的遗传和临床危险因素的最新研究进展，旨在为该疾病的诊断和干预提供更广泛的视角。
