Department of Occupational and Environmental Health, School of Public Health, Xi'an Jiaotong University Health Science Center, Xi'an, Shaanxi 710061, China; Key Laboratory of Environment and Genes Related to Diseases, Ministry of Education, China; Key Laboratory of Trace Elements and Endemic Diseases in Ministry of Health, Xi'an, Shaanxi 710061, China; Key Laboratory for Disease Prevention and Control and Health Promotion of Shaanxi Province, Xi'an, Shaanxi 710061, China.
Department of Occupational and Environmental Health, School of Public Health, Xi'an Jiaotong University Health Science Center, Xi'an, Shaanxi 710061, China; Shaanxi Provincial Institute for Endemic Disease Control, Xi'an, Shaanxi, China.
Ecotoxicol Environ Saf. 2024 Oct 1;284:117014. doi: 10.1016/j.ecoenv.2024.117014. Epub 2024 Sep 10.
The association of short-term ambient air pollution exposure with osteoarthritis (OA) outpatient visits has been unclear and no study has assessed the modifying roles of district-level characteristics in the association between ambient air pollution exposure and OA outpatient visits. We investigated the cumulative associations of ambient air pollution exposure with daily OA outpatient visits and vulnerable factors influencing the associations using data from 16 districts of Beijing, China during 2013-2019. A total of 18,351,795 OA outpatient visits were included in the analyses. An increase of 10 μg/m in fine particulate matter (PM), inhalable particulate matter (PM), nitrogen dioxide (NO), sulfur dioxide (SO), maximum 8-hour moving-average ozone (8 h-O), and 0.1 mg/m in carbon monoxide (CO) at representative lag days were associated with significant increases of 0.31 %, 0.06 %, 0.77 %, 0.87 %, 0.30 %, and 0.48 % in daily OA outpatient visits, respectively. Considerable OA outpatient visits were attributable to short-term ambient air pollution exposure. In addition, low temperature and high humidity aggravated ambient air pollution associated OA outpatient visits. District-level characteristics, such as population density, green coverage rate, and urbanization rate modified the risk of OA outpatient visits associated with air pollution exposure. These findings highlight the significance of controlling ambient air pollution during the urbanization process, which is useful in policy formation and implementation.
短期环境空气污染暴露与骨关节炎（OA）门诊就诊之间的关联尚不清楚，且尚无研究评估区级特征在环境空气污染暴露与 OA 门诊就诊之间的关联中的调节作用。我们使用了 2013 年至 2019 年期间来自中国北京 16 个区的数据，调查了环境空气污染暴露与每日 OA 门诊就诊之间的累积关联，以及影响这些关联的脆弱因素。共纳入了 1835.1795 万例 OA 门诊就诊。在代表性滞后日，细颗粒物（PM）、可吸入颗粒物（PM）、二氧化氮（NO）、二氧化硫（SO）、最大 8 小时移动平均臭氧（8h-O）和一氧化碳（CO）每增加 10μg/m，每日 OA 门诊就诊量分别显著增加 0.31%、0.06%、0.77%、0.87%、0.30%和 0.48%。相当多的 OA 门诊就诊归因于短期环境空气污染暴露。此外，低温和高湿度加剧了与空气污染有关的 OA 门诊就诊。人口密度、绿化覆盖率和城市化率等区级特征改变了与空气污染暴露相关的 OA 门诊就诊风险。这些发现强调了在城市化进程中控制环境空气污染的重要性，这对政策的制定和实施具有重要意义。
