Ren Jing-Yi, Yu Hong-Qiang, Xu Sheng, Zhou Wen-Juan, Liu Zhong-Hao
Department of Implantology, Yantai Stomatological Hospital Affiliated to Binzhou Medical University, Yantai, China; School of Stomatology, Binzhou Medical University, Yantai, China.
Department of Stomatology, Shanghai Sixth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China.
J Microbiol Immunol Infect. 2025 Apr;58(2):157-163. doi: 10.1016/j.jmii.2024.09.001. Epub 2024 Sep 6.
Streptococcus oralis, belonging to the viridans group streptococci (VGS), has been considered a component of the normal flora predominantly inhabiting the oral cavity. In recent years, a growing body of literature has revealed that dental procedures or daily tooth brushing activities can cause the spread of S. oralis from the oral cavity into various body sites leading to life-threatening opportunistic infections such as infective endocarditis (IE) and meningitis. However, very little is currently known about the pathogenicity of S. oralis. Thus, the aim of this review is to update the current understanding of the pathogenic potential of S. oralis to pave the way for the prevention and treatment of S. oralis opportunistic infections.
口腔链球菌属于草绿色链球菌群（VGS），一直被认为是主要栖息于口腔的正常菌群的组成部分。近年来，越来越多的文献表明，牙科手术或日常刷牙活动可导致口腔链球菌从口腔扩散至身体各个部位，引发如感染性心内膜炎（IE）和脑膜炎等危及生命的机会性感染。然而，目前对于口腔链球菌的致病性知之甚少。因此，本综述的目的是更新对口腔链球菌致病潜力的当前认识，为预防和治疗口腔链球菌机会性感染铺平道路。
