• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

New clinical trials in CUP and a novel paradigm in cancer classification.

作者信息

Rassy Elie, André Fabrice

机构信息

Department of Medical Oncology, Gustave Roussy, University Paris-Saclay, Villejuif, France.

CESP, INSERM U1018, Université Paris-Saclay, Villejuif, France.

出版信息

Nat Rev Clin Oncol. 2024 Dec;21(12):833-834. doi: 10.1038/s41571-024-00942-7.

DOI:10.1038/s41571-024-00942-7
PMID:39261741
Abstract
摘要

相似文献

1
New clinical trials in CUP and a novel paradigm in cancer classification.未知原发灶癌的新临床试验及癌症分类的新范式。
Nat Rev Clin Oncol. 2024 Dec;21(12):833-834. doi: 10.1038/s41571-024-00942-7.
2
Redefining cancer of unknown primary: Is precision medicine really shifting the paradigm?重新定义不明原发癌:精准医学是否真的在改变范式?
Cancer Treat Rev. 2021 Jun;97:102204. doi: 10.1016/j.ctrv.2021.102204. Epub 2021 Apr 5.
3
Carcinoma of unknown primary with a colon-cancer profile-changing paradigm and emerging definitions.原发灶不明的癌,其结肠癌特征改变模式及新出现的定义
Lancet Oncol. 2008 Jun;9(6):596-9. doi: 10.1016/S1470-2045(08)70151-7.
4
[Cancer of unknown primary-The new ESMO guidelines].[原发灶不明癌——欧洲肿瘤内科学会新指南]
Radiologie (Heidelb). 2023 May;63(5):329-335. doi: 10.1007/s00117-023-01126-7. Epub 2023 Mar 17.
5
Brain Metastasis from Unknown Primary Tumour: Moving from Old Retrospective Studies to Clinical Trials on Targeted Agents.原发灶不明的脑转移瘤:从旧的回顾性研究转向靶向药物临床试验
Cancers (Basel). 2020 Nov 12;12(11):3350. doi: 10.3390/cancers12113350.
6
Molecular assignment of tissue of origin in cancer of unknown primary may not predict response to therapy or outcome: a systematic literature review.未知原发癌组织起源的分子鉴定可能无法预测治疗反应或预后:一项系统文献综述
Cancer Treat Rev. 2009 May;35(3):221-7. doi: 10.1016/j.ctrv.2008.10.003. Epub 2008 Nov 28.
7
Carcinoma of Unknown Primary and the 8th Edition TNM Classification for Head and Neck Cancer.原发灶不明的癌和第 8 版头颈部肿瘤 TNM 分类。
Laryngoscope. 2021 Sep;131(9):E2534-E2542. doi: 10.1002/lary.29499. Epub 2021 Mar 18.
8
Systematic review of the CUP trials characteristics and perspectives for next-generation studies.CUP 试验特征的系统评价及下一代研究的展望。
Cancer Treat Rev. 2022 Jun;107:102407. doi: 10.1016/j.ctrv.2022.102407. Epub 2022 May 6.
9
[The initial CUP situation and CUP syndrome: pathological diagnostics].[原发性不明部位转移癌情况及不明部位转移癌综合征:病理诊断]
Pathologe. 2009 Dec;30 Suppl 2:161-7. doi: 10.1007/s00292-009-1193-5.
10
Progress in refining the clinical management of cancer of unknown primary in the molecular era.分子时代癌症未知原发灶临床管理的精细化进展。
Nat Rev Clin Oncol. 2020 Sep;17(9):541-554. doi: 10.1038/s41571-020-0359-1. Epub 2020 Apr 29.

引用本文的文献

1
Rethinking cancer of unknown primary: from diagnostic challenge to targeted treatment.重新审视原发灶不明的癌症:从诊断挑战到靶向治疗
Nat Rev Clin Oncol. 2025 Aug 4. doi: 10.1038/s41571-025-01060-8.

本文引用的文献

1
The ESMO Tumour-Agnostic Classifier and Screener (ETAC-S): a tool for assessing tumour-agnostic potential of molecularly guided therapies and for steering drug development.ESMO 肿瘤不可知分类器和筛查器(ETAC-S):一种用于评估基于分子靶向治疗的肿瘤不可知性和指导药物开发的工具。
Ann Oncol. 2024 Nov;35(11):936-953. doi: 10.1016/j.annonc.2024.07.730. Epub 2024 Aug 25.
2
Molecularly guided therapy versus chemotherapy after disease control in unfavourable cancer of unknown primary (CUPISCO): an open-label, randomised, phase 2 study.分子指导的治疗与疾病控制后的化疗在不利的癌症未知原发性(CUPISCO):一个开放标签,随机,2 期研究。
Lancet. 2024 Aug 10;404(10452):527-539. doi: 10.1016/S0140-6736(24)00814-6. Epub 2024 Jul 31.
3
Site-specific therapy guided by a 90-gene expression assay versus empirical chemotherapy in patients with cancer of unknown primary (Fudan CUP-001): a randomised controlled trial.
基于 90 基因表达检测的肿瘤原发灶不明患者个体化治疗与经验性化疗的比较(复旦 CUP-001):一项随机对照试验
Lancet Oncol. 2024 Aug;25(8):1092-1102. doi: 10.1016/S1470-2045(24)00313-9. Epub 2024 Jul 25.
4
Agnostic drug development revisited.重新审视不可知论药物研发。
Cancer Treat Rev. 2024 Jul;128:102747. doi: 10.1016/j.ctrv.2024.102747. Epub 2024 Apr 27.
5
Forget lung, breast or prostate cancer: why tumour naming needs to change.忘掉肺癌、乳腺癌或前列腺癌吧:肿瘤命名为何需要改变。
Nature. 2024 Feb;626(7997):26-29. doi: 10.1038/d41586-024-00216-3.
6
Systematic review of the CUP trials characteristics and perspectives for next-generation studies.CUP 试验特征的系统评价及下一代研究的展望。
Cancer Treat Rev. 2022 Jun;107:102407. doi: 10.1016/j.ctrv.2022.102407. Epub 2022 May 6.
7
Progress in refining the clinical management of cancer of unknown primary in the molecular era.分子时代癌症未知原发灶临床管理的精细化进展。
Nat Rev Clin Oncol. 2020 Sep;17(9):541-554. doi: 10.1038/s41571-020-0359-1. Epub 2020 Apr 29.
8
Randomized Phase II Trial Comparing Site-Specific Treatment Based on Gene Expression Profiling With Carboplatin and Paclitaxel for Patients With Cancer of Unknown Primary Site.随机Ⅱ期临床试验比较基于基因表达谱的肿瘤未知原发灶患者个体化治疗与卡铂联合紫杉醇的疗效
J Clin Oncol. 2019 Mar 1;37(7):570-579. doi: 10.1200/JCO.18.00771. Epub 2019 Jan 17.
9
Cancer of unknown primary site.原发灶不明的癌症。
Lancet. 2012 Apr 14;379(9824):1428-35. doi: 10.1016/S0140-6736(11)61178-1. Epub 2012 Mar 12.