Szlag Marta, Stankiewicz Magdalena, Kellas-Ślęczka Sylwia, Stąpór-Fudzińska Małgorzata, Cholewka Agnieszka, Pruefer Agnieszka, Wojcieszek Piotr
Maria Sklodowska-Curie National Research Institute of Oncology Gliwice branch Wybrzeże Armii Krajowej Street 15, 44-101 Gliwice, Poland.
Phys Imaging Radiat Oncol. 2024 Aug 17;31:100631. doi: 10.1016/j.phro.2024.100631. eCollection 2024 Jul.
The accumulated dose from sequential treatments of metachronous non-melanoma skin cancer can be assessed using image registration, although guidelines for selecting the appropriate algorithm are lacking. This study shows the impact of rigid (RIR), deformable (DIR) and deformable structure-based (SDIR) algorithms on the skin dose. DIR increased: the maximum dose (39.2 Gy vs 9.4 Gy), the dose to 0.1 cm (16.4 Gy vs 7.8 Gy) and the dose to 2 cm (7.6 Gy vs 5.7 Gy). RIR only affected the maximum dose, which increased to 17.0 Gy. SDIR correctly translated the dose maps, as none of the parameters changed significantly.
尽管缺乏选择合适算法的指南,但可使用图像配准来评估异时性非黑色素瘤皮肤癌序贯治疗的累积剂量。本研究显示了刚性(RIR)、可变形(DIR)和基于可变形结构(SDIR)算法对皮肤剂量的影响。DIR使以下剂量增加:最大剂量(39.2 Gy对9.4 Gy)、0.1 cm处的剂量(16.4 Gy对7.8 Gy)以及2 cm处的剂量(7.6 Gy对5.7 Gy)。RIR仅影响最大剂量,其增加至17.0 Gy。SDIR正确转换了剂量图,因为没有参数发生显著变化。