Hasoon, Department of Anesthesiology, University of Texas Health Science Center at Houston, Houston, Texas, USA.
Sultana, Department of General Medicine, Ramaiah Medical College, Bangalore, IN.
Psychopharmacol Bull. 2024 Aug 19;54(4):106-118.
Post-traumatic stress disorder (PTSD) stands as a pervasive psychiatric condition, exerting a profound impact on millions across the globe. Despite the availability of traditional therapeutic modalities, many individuals continue to grapple with suboptimal treatment outcomes, underscoring the urgent need for novel interventions. In recent years, stellate ganglion blocks (SGBs) have garnered attention as a promising avenue in the treatment landscape for PTSD, showcasing remarkable efficacy in ameliorating symptomatology and enhancing overall quality of life. This comprehensive review seeks to delve into the current landscape of research surrounding SGBs for PTSD, including proposed mechanisms of action, clinical efficacy across diverse patient populations, safety profile, and potential avenues for further exploration and refinement. By synthesizing the latest evidence and insights, this review aims to provide clinicians and researchers with a comprehensive understanding of the role of SGBs in PTSD management, ultimately informing clinical practice and guiding future research endeavors in this area of mental health intervention.
创伤后应激障碍（PTSD）是一种普遍存在的精神疾病，对全球数百万人产生了深远的影响。尽管有传统的治疗方法，但许多人仍然面临治疗效果不佳的问题，这凸显了对新干预措施的迫切需求。近年来，星状神经节阻滞（SGB）作为 PTSD 治疗领域的一种有前途的方法引起了关注，其在改善症状和提高整体生活质量方面显示出显著的疗效。本综述旨在深入探讨 SGB 在 PTSD 治疗中的研究现状，包括其作用机制、在不同患者群体中的临床疗效、安全性概况以及进一步探索和完善的潜在途径。通过综合最新的证据和见解，本综述旨在为临床医生和研究人员提供对 SGB 在 PTSD 管理中的作用的全面理解，最终为临床实践提供信息，并指导该领域心理健康干预的未来研究努力。
