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用于提高细菌疫苗质量控制过程性能的排队分析

Queuing analysis for improving performance in bacterial vaccine quality control process.

作者信息

Martha Sallyta Ayu, Yunani Akhmad, Setiabudi Wega, Harsanto Budi

机构信息

PT. Biofarma (Persero), Indonesia.

Faculty of Economics and Business, Universitas Padjadjaran, Indonesia.

出版信息

Vaccine X. 2024 Aug 22;20:100550. doi: 10.1016/j.jvacx.2024.100550. eCollection 2024 Oct.

Abstract

The aim of the research is to analyze and improve the performance of the vaccine quality control queuing system to reduce delays and achieve the firm's long-term goal on vaccine production capacity. The research focuses on the Bacterial Vaccine Quality Control (BVQC) at the largest vaccine manufacturers in Indonesia and Southeast Asia. The vaccines handled by BVQC include TT, DTP, BCG, BioTT, BioTd, DT, Td, and DTP-Hb-Hib. The BVQC operates a queuing system with eight servers, each assigned a fixed task. The existing system experienced delays ranging from 13 % to 61 % from January to June 2022. After identifying the queuing characteristics of the existing system, improvement proposals were suggested by modifying the assignment of the servers. This proposal was then simulated in November 2022, resulting in improved performance with no delays, a reduction in the length of the queue in the system (Lq) from 2.88 to 2.59, and a reduction in the average time spent in the system (Ws) from 0.0099 to 0.0044. The research suggests that modifying server assignments can be an effective method for improving the performance of a queuing system in vaccine quality control. This can lead to reduced delays, optimized queue lengths, and improved overall efficiency, potentially enhancing the firm's ability to meet vaccine demand in the future.

摘要

该研究的目的是分析并改善疫苗质量控制排队系统的性能,以减少延误,并实现公司在疫苗生产能力方面的长期目标。该研究聚焦于印度尼西亚和东南亚最大的疫苗制造商的细菌疫苗质量控制(BVQC)。BVQC处理的疫苗包括破伤风疫苗(TT)、白百破疫苗(DTP)、卡介苗(BCG)、生物破伤风疫苗(BioTT)、生物破伤风白喉疫苗(BioTd)、白喉破伤风疫苗(DT)、破伤风白喉疫苗(Td)以及白百破-乙肝- Hib疫苗。BVQC运行一个拥有八台服务器的排队系统,每台服务器都被分配了固定任务。2022年1月至6月,现有系统的延误率在13%至61%之间。在确定了现有系统的排队特征后,通过修改服务器的任务分配提出了改进建议。该建议随后在2022年11月进行了模拟,结果显示性能得到改善,不再有延误,系统中的队列长度(Lq)从2.88减少到2.59,系统中的平均停留时间(Ws)从0.0099减少到0.0044。该研究表明,修改服务器任务分配可以成为提高疫苗质量控制排队系统性能的有效方法。这可以减少延误、优化队列长度并提高整体效率,有可能增强公司未来满足疫苗需求的能力。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a01a/11388795/73cbc19fb2b5/gr1.jpg

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