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在监狱中接受阿片类药物使用障碍治疗的人群中对缓释丁丙诺啡的看法:一项定性研究。

Perceptions of extended-release buprenorphine among people who received medication for opioid use disorder in jail: a qualitative study.

机构信息

Department of Public Health and Community Medicine, Tufts University School of Medicine, 136 Harrison Avenue, Boston, MA, 02111, USA.

Office of Research, University of MA Chan Medical School - Baystate and Baystate Health, Springfield, MA, USA.

出版信息

Addict Sci Clin Pract. 2024 Sep 12;19(1):68. doi: 10.1186/s13722-024-00486-2.

DOI:10.1186/s13722-024-00486-2
PMID:39267138
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11395844/
Abstract

BACKGROUND

Incarceration provides an opportunity for health interventions, including opioid use disorder (OUD) treatment and prevention of opioid-related overdoses post-release. All FDA-approved forms of medication for OUD (MOUD) treatment were mandated in several Massachusetts jails in 2019, with some jails offering extended-release buprenorphine (XR-Bup). Little is known about patient perspectives on and experiences with XR-Bup in carceral settings.

METHODS

We conducted semi-structured interviews in 2022 with community-dwelling people who received MOUD during a recent incarceration in a Massachusetts jail. We asked participants about their experiences with and perspectives on XR-Bup while in jail. Qualitative data were double-coded deductively and reviewed inductively to identify emergent themes, which were structured using the Theoretical Framework of Acceptability (TFA).

RESULTS

Participants (n = 38) had a mean age of 41.5 years, were 86% male, 84% White, 24% Hispanic, and 95% continued to receive MOUD at the time of their interview, including 11% receiving XR-Bup. Participants who viewed XR-Bup favorably appreciated avoiding the taste of sublingual buprenorphine; avoiding procedural difficulties and indignities associated with daily dosing in carceral settings (e.g., mouth checks, stigmatizing treatment from correctional staff); avoiding daily reminders of their addiction; experiencing less withdrawal; having extra time for other activities, such as work; and reduction of diversion of MOUD within the jail setting. Participants who viewed XR-Bup less favorably preferred to maintain their daily dosing routine; liked daily time out of their housing unit; wanted to know what was "going into my body everyday"; and feared needles and adverse events. Participants also reported that jail clinicians used XR-Bup for patients who were previously caught diverting sublingual buprenorphine, suggesting limited patient participation in decision-making around XR-Bup initiation in some jails.

CONCLUSION

People who received MOUD in Massachusetts jails had both favorable and unfavorable views and experiences with XR-Bup. Understanding these preferences can inform protocols in jails that are considering implementation of XR-Bup treatment.

摘要

背景

监禁为健康干预提供了机会,包括阿片类药物使用障碍(OUD)治疗和预防释放后与阿片类药物相关的过量。2019 年,马萨诸塞州的几家监狱强制要求使用所有 FDA 批准的 OUD 治疗药物(MOUD),其中一些监狱提供了丁丙诺啡缓释剂(XR-Bup)。在监禁环境中,人们对 XR-Bup 的看法和体验知之甚少。

方法

我们在 2022 年对在马萨诸塞州监狱最近监禁期间接受 MOUD 的社区居民进行了半结构式访谈。我们询问了参与者在监狱期间对 XR-Bup 的体验和看法。定性数据采用双重编码演绎法进行编码,并采用归纳法进行审查,以确定出现的主题,这些主题使用可接受性理论框架(TFA)进行组织。

结果

参与者(n=38)的平均年龄为 41.5 岁,86%为男性,84%为白人,24%为西班牙裔,95%在接受采访时仍在接受 MOUD 治疗,其中 11%接受 XR-Bup。对 XR-Bup 持积极态度的参与者欣赏避免舌下丁丙诺啡的味道;避免在监禁环境中进行日常剂量治疗的程序困难和耻辱(例如,口腔检查、矫正人员的污名化治疗);避免每日提醒他们上瘾;经历较少的戒断;有额外的时间进行其他活动,例如工作;减少监狱内 MOUD 的转移。对 XR-Bup 持消极态度的参与者更喜欢维持他们的日常剂量常规;喜欢每天离开他们的住房单元;想知道“每天进入我身体的是什么”;并担心针头和不良事件。参与者还报告说,监狱临床医生将 XR-Bup 用于以前被发现转移舌下丁丙诺啡的患者,这表明在一些监狱中,患者在决定启动 XR-Bup 治疗方面的参与有限。

结论

在马萨诸塞州监狱接受 MOUD 治疗的人对 XR-Bup 有不同的看法和体验。了解这些偏好可以为正在考虑实施 XR-Bup 治疗的监狱提供协议信息。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ec42/11395844/1b5c280f8afc/13722_2024_486_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ec42/11395844/522082dde07f/13722_2024_486_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ec42/11395844/1b5c280f8afc/13722_2024_486_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ec42/11395844/522082dde07f/13722_2024_486_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ec42/11395844/1b5c280f8afc/13722_2024_486_Fig2_HTML.jpg

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本文引用的文献

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Economic Evaluation of Extended-Release Buprenorphine for Persons With Opioid Use Disorder.阿片类物质使用障碍患者的丁丙诺啡缓释片的经济学评价。
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2011-2017 年,纽约市监狱释放后,基于监狱的美沙酮或丁丙诺啡治疗阿片类药物使用障碍与过量死亡率之间的关联。
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Jail-based reentry programming to support continued treatment with medications for opioid use disorder: Qualitative perspectives and experiences among jail staff in Massachusetts.基于监狱的重新融入计划,以支持继续使用药物治疗阿片类药物使用障碍:马萨诸塞州监狱工作人员的定性观点和经验。
Int J Drug Policy. 2022 Nov;109:103823. doi: 10.1016/j.drugpo.2022.103823. Epub 2022 Aug 19.
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Medication for opioid use disorder treatment continuity post-release from jail: A qualitative study with community-based treatment providers.出狱后治疗阿片类药物使用障碍的药物治疗连续性:一项基于社区的治疗提供者的定性研究。
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Use of long-acting injectable buprenorphine in the correctional setting.在惩教环境中使用长效注射丁丙诺啡。
J Subst Abuse Treat. 2022 Nov;142:108851. doi: 10.1016/j.jsat.2022.108851. Epub 2022 Jul 29.
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Subst Abuse Treat Prev Policy. 2022 May 25;17(1):40. doi: 10.1186/s13011-022-00474-2.
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