Chang C K
J Biol Chem. 1985 Aug 15;260(17):9520-2.
Timkovich and co-workers have recently proposed a chlorin macrocycle structure for the heme d1 prosthetic group isolated from cytochrome cd1 of Pseudomonas aeruginosa and Paracoccus denitrificans (Timkovich, R., Cork, M. S., and Taylor, P. V. (1984) J. Biol. Chem. 259, 1577-1585; 15089-15093). However, this chlorin structure deduced by them is not entirely consistent with the spectral data. An alternative structure is proposed here based on the available spectral evidence. It is suggested that heme d1 in vivo is not a chlorin, but a dioxo-isobacteriochlorin having two adjacent pyrrole rings saturated.
蒂姆科维奇及其同事最近提出了一种二氢卟吩大环结构，用于从铜绿假单胞菌和反硝化副球菌的细胞色素cd1中分离出的血红素d1辅基（蒂姆科维奇，R.，科克，M. S.，和泰勒，P. V.（1984年）《生物化学杂志》259卷，1577 - 1585页；15089 - 15093页）。然而，他们推导的这种二氢卟吩结构与光谱数据并不完全一致。在此，基于现有的光谱证据提出了一种替代结构。有人认为，体内的血红素d1不是二氢卟吩，而是一种具有两个相邻吡咯环饱和的二氧代异细菌叶绿素。
