Department of Ophthalmology, University of Pennsylvania, Scheie Eye Institute, 51 North 39th Street, Philadelphia, PA 19104, USA.
Department of Ophthalmology, University of Pennsylvania, Scheie Eye Institute, 51 North 39th Street, Philadelphia, PA 19104, USA.
Infect Dis Clin North Am. 2024 Dec;38(4):795-811. doi: 10.1016/j.idc.2024.07.010. Epub 2024 Sep 12.
Our review provides an update on the current landscape of contact lens-associated microbial keratitis (MK). We discuss the prevalence and risk factors associated with MK, emphasizing the role of overnight wear, poor hygiene, and contact lens type. CL-related MK is commonly caused by bacteria, though can also be caused by fungi or protozoa. Clinical presentation involves ocular pain, redness, and vision loss, with more specific presenting symptoms based on the culprit organism. Treatment strategies encompass prevention through proper hygiene and broad-spectrum antibiotic, antifungal, or antiprotozoal therapy, with surgical management reserved for severe recalcitrant cases.
我们的综述提供了接触镜相关微生物角膜炎 (MK) 现状的最新信息。我们讨论了与 MK 相关的患病率和风险因素,强调了过夜佩戴、不良卫生习惯和接触镜类型的作用。CL 相关的 MK 通常由细菌引起,但也可由真菌或原生动物引起。临床表现包括眼部疼痛、发红和视力下降,根据病原体的不同,还有更具体的表现症状。治疗策略包括通过适当的卫生和广谱抗生素、抗真菌药或抗原生动物药物进行预防,对于严重难治性病例则保留手术治疗。