Manee Manee M, Al-Shomrani Badr M, Alqahtani Fahad H
National Center for Bioinformatics, King Abdulaziz City for Science and Technology, Riyadh 11442, Saudi Arabia.
Advanced Agricultural and Food Technologies Institute, King Abdulaziz City for Science and Technology, Riyadh 11442, Saudi Arabia.
Animals (Basel). 2024 Aug 24;14(17):2460. doi: 10.3390/ani14172460.
The Camelidae family, ranging from southwest Asia to north Africa, South America, and Australia, includes key domesticated species adapted to diverse environments. Among these, the Arabian camel () is vital to the cultural and economic landscape of the Arabian Peninsula. This review explores the mitochondrial DNA of the dromedary camel, focusing on the D-loop region to understand its genetic diversity, maternal inheritance, and evolutionary history. We aim to investigate the unique characteristics of Arabian camel mtDNA, analyze the D-loop for genetic diversity and maternal lineage patterns, and explore the implications of mitochondrial genomic studies for camel domestication and adaptation. Key findings on mtDNA structure and variation highlight significant genetic differences and adaptive traits. The D-loop, essential for mtDNA replication and transcription, reveals extensive polymorphisms and haplotypes, providing insights into dromedary camel domestication and breeding history. Comparative analyses with other camelid species reveal unique genetic signatures in the Arabian camel, reflecting its evolutionary and adaptive pathways. Finally, this review integrates recent advancements in mitochondrial genomics, demonstrating camel genetic diversity and potential applications in conservation and breeding programs. Through comprehensive mitochondrial genome analysis, we aim to enhance the understanding of Camelidae genetics and contribute to the preservation and improvement of these vital animals.
骆驼科分布于从亚洲西南部到北非、南美洲和澳大利亚,其中包括适应各种环境的重要家养物种。在这些物种中,阿拉伯骆驼(单峰驼)对阿拉伯半岛的文化和经济格局至关重要。本综述探讨了单峰骆驼的线粒体DNA,重点关注D环区域,以了解其遗传多样性、母系遗传和进化历史。我们旨在研究阿拉伯骆驼线粒体DNA的独特特征,分析D环的遗传多样性和母系谱系模式,并探讨线粒体基因组研究对骆驼驯化和适应的意义。关于线粒体DNA结构和变异的主要发现突出了显著的遗传差异和适应性特征。对线粒体DNA复制和转录至关重要的D环揭示了广泛的多态性和单倍型,为单峰骆驼的驯化和育种历史提供了见解。与其他骆驼科物种的比较分析揭示了阿拉伯骆驼独特的遗传特征,反映了其进化和适应途径。最后,本综述整合了线粒体基因组学的最新进展,展示了骆驼的遗传多样性及其在保护和育种计划中的潜在应用。通过全面的线粒体基因组分析,我们旨在增进对骆驼科遗传学的理解,并为保护和改良这些重要动物做出贡献。