Blakeslee D B, Becker G D, Simpson G T, Patten D H, Sprengelmeyer J
Otolaryngol Head Neck Surg. 1985 Jun;93(3):361-5. doi: 10.1177/019459988509300314.
Lymph node imaging has been helpful in managing patients with lymphoma, melanoma, and breast cancer. To evaluate 38 patients with head and neck cancers, 99mTc minicolloid was injected adjacent to the tumor and into a similar area on the uninvolved side. Lymphoscintigraphy of the neck was performed at 3- and 5-hour intervals after injection and bilateral cervical lymphatic drainage was observed. Each patient then underwent a neck dissection. The pathologic node findings were then correlated with the neck scans. Results confirmed that cervical lymphatic drainage is unpredictable in 50% of the patients once the channels are involved with metastatic disease. Lymphoscintigraphy is not a reliable method of detecting early metastatic cervical carcinoma.
淋巴结成像有助于淋巴瘤、黑色素瘤和乳腺癌患者的管理。为评估38例头颈部癌症患者，将99mTc微胶体注射到肿瘤旁以及未受累侧的类似区域。注射后每隔3小时和5小时进行颈部淋巴闪烁扫描，并观察双侧颈部淋巴引流情况。然后每位患者均接受颈部清扫术。之后将病理淋巴结检查结果与颈部扫描结果进行对比。结果证实，一旦淋巴管受累于转移性疾病，50%的患者颈部淋巴引流是不可预测的。淋巴闪烁扫描不是检测早期转移性宫颈癌的可靠方法。
