Zimmermann Julian Alexander, Kleemann Sarah, Storp Jens Julian, Weich Cedric, Merté Ralph-Laurent, Eter Nicole, Brücher Viktoria Constanze
Department of Ophthalmology, University of Muenster Medical Center, 48149 Muenster, Germany.
J Clin Med. 2024 Sep 9;13(17):5333. doi: 10.3390/jcm13175333.
: Glaucoma, one leading cause of irreversible vision loss worldwide, is primarily caused by elevated intraocular pressure (IOP). Recently, minimally invasive glaucoma surgeries (MIGSs) have become popular due to their shorter surgical times, tissue-sparing nature, and faster recovery. One such MIGS, the Hydrus nickel-titanium alloy Microstent, helps lower IOP by improving aqueous humor outflow. The NIDEK GS-1 automated 360° gonioscope provides advanced imaging of the chamber angle for evaluation and documentation. The aim of this study was to test automated 360° gonioscopy for the detection of postoperative positional variations after Hydrus Microstent implantation. This study is the largest to date to evaluate post-op positioning of the Hydrus Microstent using the NIDEK GS-1. : This study analyzed postoperative outcomes and stent location in eyes diagnosed with mild to moderate glaucoma that underwent Hydrus Microstent implantation with or without phacoemulsification. Patients with prior IOP-lowering surgery or vitrectomy were excluded. Analyses of the postoperative Hydrus Microstent position were based on the evaluation of automated 360° gonioscopy images. : Twenty-three eyes were included in the study, and all showed a reduction in IOP and a decrease in antiglaucomatous drop use postoperatively. Postoperative gonoscopic images showed variations in implant position. In all cases, the proximal inlet was clearly visible in the anterior chamber. The degree of protrusion into the anterior chamber was variable. The distal tip of the stent was visible behind the trabecular meshwork in Schlemm's canal in five cases, in the anterior chamber in one case, and not visible in seven cases. In no case did postoperative alterations in the position of the implant lead to explantation. : This study demonstrated that the Hydrus Microstent can effectively lower IOP even in the presence of postoperative positional variations. Automated 360° gonioscopy was found to be a useful tool to verify and document the postoperative position of the implant. Positional changes did not require device explantation in any of the cases evaluated.
青光眼是全球不可逆视力丧失的主要原因之一,主要由眼内压(IOP)升高引起。最近,微创青光眼手术(MIGS)因其手术时间短、对组织损伤小和恢复快而受到欢迎。一种这样的MIGS,Hydrus镍钛合金微支架,通过改善房水流出有助于降低眼内压。NIDEK GS-1自动360°前房角镜可提供前房角的先进成像,用于评估和记录。本研究的目的是测试自动360°前房角镜检查在检测Hydrus微支架植入术后位置变化方面的效果。本研究是迄今为止使用NIDEK GS-1评估Hydrus微支架术后位置的最大规模研究。:本研究分析了接受或未接受超声乳化白内障吸除术的轻至中度青光眼患者在植入Hydrus微支架后的术后结果和支架位置。既往接受过降眼压手术或玻璃体切除术的患者被排除在外。对术后Hydrus微支架位置的分析基于对自动360°前房角镜图像的评估。:该研究纳入了23只眼,所有眼术后眼压均降低,抗青光眼药物使用量减少。术后前房角镜图像显示植入物位置存在变化。在所有病例中,前房内均可清晰看到近端入口。前房内突出程度各不相同。在5例中,支架远端尖端可见于施莱姆管内小梁网后方,1例可见于前房内,7例不可见。在任何病例中,植入物位置的术后改变均未导致植入物取出。:本研究表明,即使存在术后位置变化,Hydrus微支架仍能有效降低眼压。自动360°前房角镜检查被发现是一种用于验证和记录植入物术后位置的有用工具。在所评估的任何病例中,位置变化均不需要取出装置。