Wolf Claude, Juchem Deborah, Koster Anna, Pilloy Wilfrid
Department of Engineering, University of Luxembourg, 6 Rue Coudenhove-Kalergi, L-1359 Luxembourg, Luxembourg.
Department of Nuclear Medicine, Sefako Makgatho University, Ga-Rankuwa 0208, South Africa.
Materials (Basel). 2024 Aug 27;17(17):4241. doi: 10.3390/ma17174241.
Additive manufacturing (AM) allows the creation of customized designs for various medical devices, such as implants, casts, and splints. Amongst other AM technologies, fused filament fabrication (FFF) facilitates the production of intricate geometries that are often unattainable through conventional methods like subtractive manufacturing. This study aimed to develop a methodology for substituting a pathological talus bone with a personalized one created using additive manufacturing. The process involved generating a numerical parametric solid model of the specific anatomical region using computed tomography (CT) scans of the corresponding healthy organ from the patient. The healthy talus served as a mirrored template to replace the defective one. Structural simulation of the model through finite element analysis (FEA) helped compare and select different materials to identify the most suitable one for the replacement bone. The implant was then produced using FFF technology. The developed procedure yielded commendable results. The models maintained high geometric accuracy, while significantly reducing the computational time. PEEK emerged as the optimal material for bone replacement among the considered options and several specimens of talus were successfully printed.
增材制造（AM）能够为各种医疗设备创建定制设计，如植入物、石膏模型和夹板。在其他增材制造技术中，熔融沉积成型（FFF）有助于制造复杂的几何形状，而这些形状通常是传统的减法制造等方法无法实现的。本研究旨在开发一种方法，用增材制造创建的个性化距骨替代病理性距骨。该过程包括使用患者相应健康器官的计算机断层扫描（CT）生成特定解剖区域的数值参数实体模型。健康的距骨作为镜像模板来替代有缺陷的距骨。通过有限元分析（FEA）对模型进行结构模拟，有助于比较和选择不同材料，以确定最适合替代骨的材料。然后使用FFF技术制造植入物。所开发的程序产生了值得称赞的结果。模型保持了较高的几何精度，同时显著减少了计算时间。在考虑的选项中，聚醚醚酮（PEEK）成为骨替代的最佳材料，并且成功打印了多个距骨标本。
