Department of Pediatrics, Children's Hospital Los Angeles and Keck School of Medicine of USC, Center for Endocrinology, Diabetes and Metabolism, 4650 Sunset Boulevard, Los Angeles, CA 90027, USA.
Department of Pediatrics, Children's Hospital Los Angeles and Keck School of Medicine of USC, Center for Endocrinology, Diabetes and Metabolism, 4650 Sunset Boulevard, Los Angeles, CA 90027, USA.
Gastrointest Endosc Clin N Am. 2024 Oct;34(4):781-804. doi: 10.1016/j.giec.2024.06.004. Epub 2024 Aug 14.
Pediatric obesity continues to be an omnipresent disease; 1 in 5 children and adolescents have obesity in the United States. The comorbidities associated with youth-onset obesity tend to have a more severe disease progression in youth compared to their adult counterparts with the same obesity-related condition. A comorbidity of focus in this study is metabolism-associated steatotic liver disease (MASLD), which has rapidly evolved into the most common liver disease seen in the pediatric population. A direct association exists between the treatment of MASLD and the treatment of pediatric obesity. The current evidence supports that obesity treatment is safe and effective.
儿科肥胖仍然是一种普遍存在的疾病；在美国，每 5 个儿童和青少年中就有 1 个肥胖。与青少年期肥胖相关的合并症往往比患有相同肥胖相关疾病的成年人进展更为严重。本研究关注的合并症之一是代谢相关脂肪性肝病（MASLD），它已迅速成为儿科人群中最常见的肝病。MASLD 的治疗与儿科肥胖的治疗之间存在直接关联。目前的证据表明肥胖治疗是安全有效的。
