Orthopaedic Department, Peking University Third Hospital, Haidian District, No. 49 North Garden Road, Beijing, 100191, China.
Peking University Health Science Center, Haidian District, No. 38 Xueyuan Road, Beijing, 100191, China.
BMC Musculoskelet Disord. 2024 Sep 14;25(1):738. doi: 10.1186/s12891-024-07842-y.
Paraspinal muscle degeneration occurs with age; however, it is unknown whether strength and endurance change with muscle cross-sectional area (CSA) and fatty infiltration (FI) parameters in Chinese healthy individuals.
A total of 94 asymptomatic Chinese volunteers were enrolled in this study. The participants were divided into three groups: young (20-39 years old, n = 27), middle-aged (40-59 years old, n = 49), and elderly (≥ 60 years old, n = 18). CSA and FI of the psoas (PS), quadratus lumborum (QL), multifidus (MF), and erector spinae (ES) were measured using magnetic resonance imaging. The Bionix Sim3 Pro was used to evaluate the maximum isometric torque and the Ito test to evaluate endurance.
The CSA of the PS and ES in the elderly group was smaller than those in the other groups, while the CSA of QL in the young group was larger than that in the other groups. There were differences in the MF and ES FI among the three groups. The maximum isometric torque and endurance test time decreased with increasing age; however, these differences were not statistically significant. Maximum isometric torque positively correlated with the average paraspinal muscle CSA and negatively correlated with the torque and FI of the MF and ES muscles. The endurance test was found to be positively correlated with the FCSA of the MF and to be negatively correlated with the FI of the MF and ES. PS and QL can predict the maximum isometric torque, and MF and PS can predict the endurance time.
MF and ES showed earlier degeneration than PS and QL. MF is the first paraspinal muscle to undergo functional area atrophy, and it plays an important role in the endurance test. The maximum moment of equal length in all directions of the lumbar spine is not completely symmetrical, but it is correlated with the imaging parameters of the paraspinal muscles. QL and PS were more activated in the lumbar activity.
The study was registered in Chinese Clinical Trial Registry and the registration number is ChiCTR2000039073 on 15/10/2020 ( https://www.chictr.org.cn/showproj.html?proj=62785 ). Ethical Approval was obtained from the Peking University Third Hospital Medical Science Research Ethics Committee (IRB00006761-M2020305).
脊柱旁肌肉会随着年龄的增长而退化；然而，在中国健康人群中，肌肉横截面积（CSA）和脂肪浸润（FI）参数与力量和耐力的变化关系尚不清楚。
本研究共纳入 94 名无症状的中国志愿者。参与者被分为三组：青年组（20-39 岁，n=27）、中年组（40-59 岁，n=49）和老年组（≥60 岁，n=18）。使用磁共振成像测量腰大肌（PS）、竖脊肌（QL）、多裂肌（MF）和竖脊肌（ES）的 CSA 和 FI。使用 Bionix Sim3 Pro 评估最大等长扭矩，使用 Ito 测试评估耐力。
老年组 PS 和 ES 的 CSA 小于其他组，而青年组 QL 的 CSA 大于其他组。三组之间 MF 和 ES 的 FI 存在差异。最大等长扭矩和耐力测试时间随年龄增长而降低，但差异无统计学意义。最大等长扭矩与平均脊柱旁肌肉 CSA 呈正相关，与 MF 和 ES 肌肉的扭矩和 FI 呈负相关。耐力测试与 MF 的 FCSA 呈正相关，与 MF 和 ES 的 FI 呈负相关。PS 和 QL 可预测最大等长扭矩，MF 和 PS 可预测耐力时间。
MF 和 ES 比 PS 和 QL 更早出现退化。MF 是第一个发生功能区萎缩的脊柱旁肌肉，在耐力测试中起重要作用。腰椎各向等长最大力矩不完全对称，但与脊柱旁肌肉的影像学参数相关。QL 和 PS 在腰椎活动中更活跃。
本研究在中国临床试验注册中心注册，注册号为 ChiCTR2000039073（2020 年 10 月 15 日）（https://www.chictr.org.cn/showproj.html?proj=62785）。本研究获得了北京大学第三医院医学科学研究伦理委员会（IRB00006761-M2020305）的批准。
