Weber W J, Boothe H W, Brassard J A, Hobson H P
Am J Vet Res. 1985 Jun;46(6):1309-15.
Comparison was made of the healing of sutured prescrotal urethral incisions (12 dogs) with that of nonsutured incisions (6 dogs). Comparison was also made of the healing of 5-0 polyglactin 910-sutured urethral incisions (6 dogs) with that of 5-0 polydioxanone-sutured incisions (6 dogs). Three dogs from each treatment group were euthanatized 3 weeks and 6 weeks after the surgical procedure. Surgical sites were examined grossly, and urethral circumference measurements were taken at 3 locations (surgical site, 1 cm cranially, and 1 cm caudally). Transverse sections of the surgical sites were prepared and examined by light microscopy. Hemorrhage occurred postoperatively in dogs in which the incisions were not sutured. The surgical sites from the 6 dogs in which incisions healed by second intention had more fibrosis and less inflammation than did those that were sutured. There was little difference between incisions sutured with polyglactin 910 and those sutured with polydioxanone suture material. Postoperative urethral stricture formation did not occur in any of the dogs.
对阴囊前尿道缝合切口（12只犬）和未缝合切口（6只犬）的愈合情况进行了比较。还对5-0聚乙醇酸910缝合的尿道切口（6只犬）和5-0聚二氧杂环己酮缝合的切口（6只犬）的愈合情况进行了比较。每个治疗组的3只犬在手术3周和6周后实施安乐死。对手术部位进行大体检查，并在3个位置（手术部位、头侧1 cm和尾侧1 cm）测量尿道周长。制备手术部位的横切面并通过光学显微镜检查。未缝合切口的犬术后发生出血。6只切口通过二期愈合的犬的手术部位比缝合的犬有更多的纤维化和更少的炎症。聚乙醇酸910缝合的切口与聚二氧杂环己酮缝合材料缝合的切口之间差异不大。所有犬均未发生术后尿道狭窄形成。
