一款个性化信息提供与运动指导应用程序对更年期女性生活质量功效的验证

Validation of the efficacy of a personalized information-provision and exercise-coaching app on the quality of life of menopausal women.

作者信息

Kim Na Yeon, Kim Da Seul, Han Doug Hyun, Hong Ji Sun, Shim Yoojin, Yoon Youn Jung, Kim Hee Jun, Kim Sun Mi

机构信息

Department of Psychiatry, College of Medicine, Chung-Ang University, 84 Heukseok-ro, Dongjak-gu, Seoul 06974, Republic of Korea.

Department of Obstetrics and Gynecology, College of Medicine, Chung-Ang University, 84 Heukseok-ro, Dongjak-gu, Seoul 06974, Republic of Korea.

出版信息

Maturitas. 2024 Nov;189:108113. doi: 10.1016/j.maturitas.2024.108113. Epub 2024 Sep 6.

DOI:10.1016/j.maturitas.2024.108113

PMID:39278097

Abstract

OBJECTIVES

Menopausal symptoms severely impact women's quality of life (QoL). Digital health interventions provide an accessible, personalized alternative for managing menopausal symptoms. In this study, we validated the Menopause Assistant Manager (MAMA®; Hudit, Seoul, S. Korea) app developed to provide personalized information, exercise coaching, and management of appointments and medications to menopausal women, and evaluated its efficacy on their QoL.

STUDY DESIGN

This nonrandomized interventional trial enrolled 48 peri- and postmenopausal women into experimental (MAMA) and control (Waitlist) groups (n = 24 each). Participants in the MAMA group used the app for 8 weeks, whereas the Waitlist group received no intervention. Both groups continued their usual treatments.

MAIN OUTCOME MEASURES

Clinical assessments at baseline and study completion included the World Health Organization Quality of Life Brief Version (WHOQOL-BREF), Menopause Rating Scale, Patient Health Questionnaire-9, Generalized Anxiety Disorder-7 (GAD-7), Patient Health Questionnaire-15 (PHQ-15), Menopause Emotional Symptom Questionnaire, and Subjective Memory Complaints Questionnaire.

RESULTS

Compared with the Waitlist group, the MAMA group showed postintervention improvements in WHOQOL-BREF physical health (F = 4.84, P = .03) and environmental (F = 5.01, P = .03) domains and GAD-7 (F = 5.53, P = .02) and PHQ-15 (F = 4.14, P = .048) scores. Changes in WHOQOL-BREF physical health scores negatively correlated with PHQ-15 scores (ρ = -0.53, P = .004).

CONCLUSION

By increasing treatment accessibility, the app improved physical and environmental QoL and reduced anxiety and somatic symptoms. App-based exercise coaching alleviated somatic symptoms, and the in-app psychological content reduced anxiety by normalizing menopausal symptoms, providing accurate information, decreasing uncertainty, and improving symptom perception.

TRIAL REGISTRATION

Clinical Research Information Service KCT 0008603; https://cris.nih.go.kr/cris/search/detailSearch.do?seq=25078&status=5&seq_group=25078&search_page=M.

摘要

目的

更年期症状严重影响女性的生活质量（QoL）。数字健康干预为管理更年期症状提供了一种可及的、个性化的选择。在本研究中，我们验证了为更年期女性提供个性化信息、运动指导以及预约和用药管理而开发的更年期助理管理器（MAMA®；韩国首尔Hudit公司）应用程序，并评估了其对女性生活质量的疗效。

研究设计

这项非随机干预试验将48名围绝经期和绝经后女性纳入实验组（MAMA组）和对照组（候补名单组）（每组n = 24）。MAMA组的参与者使用该应用程序8周，而候补名单组未接受任何干预。两组均继续其常规治疗。

主要结局指标

基线和研究结束时的临床评估包括世界卫生组织生活质量简表（WHOQOL - BREF）、更年期评定量表、患者健康问卷 - 9、广泛性焦虑障碍 - 7（GAD - 7）、患者健康问卷 - 15（PHQ - 15）、更年期情绪症状问卷和主观记忆障碍问卷。

结果

与候补名单组相比，MAMA组在WHOQOL - BREF的身体健康（F = 4.84，P = 0.03）和环境（F = 5.01，P = 0.03）领域以及GAD - 7（F = 5.53，P = 0.02）和PHQ - 15（F = 4.14，P = 0.048）评分方面干预后有所改善。WHOQOL - BREF身体健康评分的变化与PHQ - 15评分呈负相关（ρ = -0.53，P = 0.004）。