Liu Cuiting, Chen Liangying, Zheng Jiansheng, Yu Xuefen, Gao Huiting, Qiu Lijuan, Liu Cuiping
School of Nursing, Putian University, Putian, China.
School of Basic Medicine, Putian University, Putian, China.
J Adv Nurs. 2025 Jun;81(6):3013-3024. doi: 10.1111/jan.16450. Epub 2024 Sep 15.
To identify distinct profiles of fear of cancer recurrence (FCR) among breast cancer patients of reproductive age, investigate the relationship between these profiles and reproductive concerns and explore potential risk factors encompassing sociodemographic, clinical and reproductive characteristics.
A cross-sectional study was conducted from January 2022 to September 2022.
A convenience sample of 210 reproductive-aged breast cancer patients completed a questionnaire that included a general information section, the Fear of Progression Questionnaire-Short Form (FoP-Q-SF) and the Reproductive Concerns After Cancer Scale (RCAC). Latent profile analysis was conducted using the scores of the 12 items from the FoP-Q-SF as explicit variables, while univariate and multiple logistic regression analyses were employed for statistical analysis.
Three latent variables were identified: low FCR-stable group (27.6%), moderate FCR-uneasy group (17.2%) and high FCR-intense group (55.2%). This study found that FCR was predicted by age, education level, cancer stage, chemotherapy and fertility intention. Furthermore, patients with heightened reproductive concerns exhibited a higher likelihood of belonging to the high FCR-intense group.
These findings indicate that FCR varies among breast cancer patients of reproductive age and demonstrates individual differences.
Early identification of FCR patterns in patients is crucial for medical professionals, with particular attention given to those in the high-intensity FCR group. Tailored prevention and care strategies should be implemented based on the unique characteristics and influencing factors associated with different potential categories of FCR among patients of childbearing age with breast cancer.
No patient or public contribution.
识别育龄期乳腺癌患者中不同的癌症复发恐惧（FCR）特征，研究这些特征与生殖方面担忧之间的关系，并探索包括社会人口统计学、临床和生殖特征在内的潜在风险因素。
于2022年1月至2022年9月进行了一项横断面研究。
选取210名育龄期乳腺癌患者作为便利样本，完成一份问卷，问卷包括一般信息部分、癌症进展恐惧问卷简表（FoP-Q-SF）和癌症后生殖担忧量表（RCAC）。以FoP-Q-SF中12个条目的得分作为显性变量进行潜在类别分析，同时采用单因素和多因素逻辑回归分析进行统计分析。
识别出三个潜在类别：低FCR-稳定组（27.6%）、中度FCR-不安组（17.2%）和高FCR-强烈组（55.2%）。本研究发现，FCR可由年龄、教育水平、癌症分期、化疗和生育意愿预测。此外，生殖方面担忧较高的患者更有可能属于高FCR-强烈组。
这些发现表明，FCR在育龄期乳腺癌患者中存在差异，并表现出个体差异。
对医疗专业人员而言，早期识别患者的FCR模式至关重要，尤其要关注高强度FCR组的患者。应根据乳腺癌育龄期患者中不同潜在FCR类别相关的独特特征和影响因素，实施针对性的预防和护理策略。
无患者或公众参与。
