特应性皮炎瘙痒的辅助治疗。

Adjunctive Management of Itch in Atopic Dermatitis.

机构信息

Dr. Phillip Frost Department of Dermatology and Cutaneous Surgery, Miami Itch Center, University of Miami Miller School of Medicine, 5555 Ponce de Leon Boulevard, Coral Gables, FL 33146, USA.

出版信息

Dermatol Clin. 2024 Oct;42(4):577-589. doi: 10.1016/j.det.2024.04.008. Epub 2024 Jun 4.

DOI:10.1016/j.det.2024.04.008

PMID:39278711

Abstract

Atopic dermatitis (AD) is a chronic inflammatory skin condition that can be difficult to treat due to a complex etiology and diverse clinical presentations. Itch is the most common symptom associated with AD with profound negative impact on quality of life. Thus, the adjunctive management of itch in patients with AD is needed to control and reduce disease burden. Supplemental treatment options are continuously emerging and undergoing testing in clinical trials. This article summarizes the latest data on topical and systemic adjunctive therapies for AD safety and efficacy in reducing itch.

摘要

特应性皮炎（AD）是一种慢性炎症性皮肤病，由于病因复杂，临床表现多样，因此治疗较为困难。瘙痒是与 AD 相关的最常见症状，对生活质量有深远的负面影响。因此，需要对 AD 患者进行瘙痒的辅助管理，以控制和减轻疾病负担。补充治疗方案不断涌现，并在临床试验中进行测试。本文总结了最新数据，介绍了用于 AD 的局部和全身辅助疗法在减轻瘙痒方面的安全性和疗效。