Calmi D, Pagnoni B, Tiengo M, Ravanelli A, Savio G, Dal Prà M L
Arzneimittelforschung. 1985;35(6):981-3.
A comparative study between nefopam (Acupan) and pentazocine was carried out in 90 patients for treatment of postoperative pain following gynaecological operations. The results show that nefopam has an analgesic activity comparable with that of pentazocine, but its duration of action seems to be longer-lasting, even if with a longer period of latency. At equieffective analgesic action, nefopam shows a lower interference with the respiratory function. As far as side-effects are concerned a significant increase in drowsiness was observed with both types of treatment; sweating was observed only in nefopam group.
对90例妇科手术后疼痛患者进行了奈福泮（阿克扑）与喷他佐辛的对比研究。结果表明，奈福泮具有与喷他佐辛相当的镇痛活性，但其作用持续时间似乎更长，尽管潜伏期较长。在等效镇痛作用下，奈福泮对呼吸功能的干扰较小。就副作用而言，两种治疗均观察到嗜睡显著增加；仅在奈福泮组观察到出汗。
