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弥漫性肺淋巴管瘤病作为前纵隔肿块的鉴别诊断。

Diffuse pulmonary lymphangiomatosis as a differential diagnosis of anterior mediastinal mass.

作者信息

Salcedo Miranda Diego, Galvis Jorge Roberto, Téllez Rodríguez Luis Jaime, Garzón Ramírez Juan Carlos, Ariza Traslaviña Julián

机构信息

Thoracic Surgery, National Cancer Institute - El Bosque University, Bogotá, 111511, Colombia.

General Surgery, El Bosque University, Bogotá, 110121, Colombia.

出版信息

J Surg Case Rep. 2024 Sep 12;2024(9):rjae577. doi: 10.1093/jscr/rjae577. eCollection 2024 Sep.

DOI:10.1093/jscr/rjae577
PMID:39280023
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11393567/
Abstract

Diffuse pulmonary lymphangiomatosis (DLP) is an extremely rare silent disease, characterized by proliferation and thickening of abnormal pulmonary, pleural, and mediastinal soft tissue lymphatic channels. Its clinical presentation is nonspecific symptoms such as cough, dyspnea, and hemoptysis. Tomographic findings for DLP include thickening of the interlobular septa and peribronchovascular interstitium and ground glass opacities. Nevertheless, the anterior mediastinal mass, associated with thickening of interlobular septa and peribronchovascular interstitial, ground glass opacities, pleural effusion, diffuse infiltration of the mediastinum and pleural thickening in a patient with lymphangiomas, DLP should be suspected as a differential diagnosis.

摘要

弥漫性肺淋巴管瘤病（DLP）是一种极其罕见的隐匿性疾病，其特征为异常的肺、胸膜和纵隔软组织淋巴管通道增生和增厚。其临床表现为咳嗽、呼吸困难和咯血等非特异性症状。DLP的断层扫描表现包括小叶间隔和支气管血管周围间质增厚以及磨玻璃影。然而，对于一名患有淋巴管瘤的患者，若出现前纵隔肿块，伴有小叶间隔和支气管血管周围间质增厚、磨玻璃影、胸腔积液、纵隔弥漫性浸润和胸膜增厚，则应怀疑为DLP进行鉴别诊断。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1581/11393567/dc83d44c9bd4/rjae577f6.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1581/11393567/885b2c981a4e/rjae577f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1581/11393567/87e2ed6e28e0/rjae577f2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1581/11393567/717fef2d30ca/rjae577f3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1581/11393567/c9697330f533/rjae577f4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1581/11393567/c83ecbda524b/rjae577f5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1581/11393567/dc83d44c9bd4/rjae577f6.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1581/11393567/885b2c981a4e/rjae577f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1581/11393567/87e2ed6e28e0/rjae577f2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1581/11393567/717fef2d30ca/rjae577f3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1581/11393567/c9697330f533/rjae577f4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1581/11393567/c83ecbda524b/rjae577f5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1581/11393567/dc83d44c9bd4/rjae577f6.jpg

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本文引用的文献

1
Diffuse pulmonary lymphangiomatosis involving lungs and mediastinal soft tissue.弥漫性肺淋巴管肌瘤病累及肺和纵隔软组织。
Am J Med Sci. 2022 Jul;364(1):118-123. doi: 10.1016/j.amjms.2022.03.015. Epub 2022 Apr 9.
2
Effective Initial Treatment of Diffuse Pulmonary Lymphangiomatosis with Sirolimus and Propranolol: A Case Report.弥漫性肺淋巴管肌瘤病采用西罗莫司和普萘洛尔有效初始治疗：病例报告。
Medicina (Kaunas). 2021 Nov 29;57(12):1308. doi: 10.3390/medicina57121308.
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A case of diffuse pulmonary lymphangiomatosis with a venous anomaly presenting with acute respiratory failure and hemoptysis.
一例伴有静脉异常的弥漫性肺淋巴管瘤病，表现为急性呼吸衰竭和咯血。
Respir Med Case Rep. 2020 Oct 7;31:101243. doi: 10.1016/j.rmcr.2020.101243. eCollection 2020.
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Late diagnosis of generalized lymphangiomatosis in a woman presenting with respiratory distress.一名出现呼吸窘迫的女性患者的全身性淋巴管瘤病的晚期诊断
Radiol Case Rep. 2020 Jun 9;15(8):1189-1193. doi: 10.1016/j.radcr.2020.05.021. eCollection 2020 Aug.
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Diffuse pulmonary lymphangiomatosis: A rare case report in an adult.弥漫性肺淋巴管瘤病：一例成人罕见病例报告
Medicine (Baltimore). 2019 Oct;98(43):e17349. doi: 10.1097/MD.0000000000017349.
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Lymphangiomatosis in a 14-year-old female presenting with chylothorax and multiple cystic lesions.一名14岁女性淋巴管瘤病患者，表现为乳糜胸和多发囊性病变。
Radiol Case Rep. 2018 Jun 7;13(4):782-787. doi: 10.1016/j.radcr.2018.05.002. eCollection 2018 Aug.
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