Gramling Grant, Wu Michelle, Kolta Bishoy, Alleyne Shirley
Osteopathic Medicine, Nova Southeastern University Dr. Kiran C. Patel College of Osteopathic Medicine, Clearwater, USA.
Psychiatry Residency Program, Lakeland Regional Health, Lakeland, USA.
Cureus. 2024 Aug 16;16(8):e67001. doi: 10.7759/cureus.67001. eCollection 2024 Aug.
Capgras syndrome (CS) is a type of delusional misidentification syndrome where an individual is under the impression that a person they know has been switched with an identical imposter. One theory for the development of CS is a disturbance among the frontal, limbic, and temporal areas, which creates an alteration in an individual's ability to recognize a person's face and provoke a response emotionally. The primary risk factors for the development of CS include having a neurological disorder and a diagnosis of schizophrenia. We present a case of a 39-year-old male with a past medical history of traumatic brain injury and familial history of schizophrenia who presented to the Emergency Department with paranoia and the belief that his father had been switched with an imposter. After ruling out organic causes, he was stabilized on olanzapine before discharge to outpatient follow-up. This case highlights the importance of prompt recognition of the symptomatology associated with CS and treatment with olanzapine for a favorable outcome.
卡普格拉综合征（CS）是一种妄想性错认综合征，患者会认为他们认识的人被一个一模一样的冒名顶替者替换了。关于CS发病的一种理论是额叶、边缘叶和颞叶区域出现紊乱，这会改变个体识别他人面孔的能力，并引发情感反应。CS发病的主要风险因素包括患有神经疾病和被诊断为精神分裂症。我们报告一例39岁男性病例，他有创伤性脑损伤病史和精神分裂症家族史，因妄想以及认为自己的父亲被冒名顶替者替换而就诊于急诊科。排除器质性病因后，他在出院接受门诊随访前使用奥氮平病情稳定。该病例凸显了及时识别与CS相关症状并使用奥氮平治疗以获得良好预后的重要性。
