七鳃鳗中枢神经系统中的促甲状腺激素释放激素

Thyrotropin-releasing hormone in lamprey central nervous system.

作者信息

Youngs L J, Winokur A, Selzer M E

出版信息

Brain Res. 1985 Jul 8;338(1):177-80. doi: 10.1016/0006-8993(85)90264-1.

Abstract

Thyrotropin-releasing hormone (TRH) levels were measured by radioimmunoassay in the CNS of larval and adult sea lampreys and adult river lampreys. In larval sea lampreys, the pituitary complex contained approx. 609 pg TRH/mg, brain contained 43.5 +/- 5.5 pg/mg (mean +/- S.E.M.) while the spinal cord contained 11.2 +/- 2.3 pg/mg. Corresponding levels in the adult sea and river lampreys were similar. Complete spinal transection did not significantly alter TRH levels below the lesion. Thus, the spinal cord contains TRH independent of supraspinal axonal projections.

摘要

通过放射免疫分析法测定了幼虫和成年海七鳃鳗以及成年河七鳃鳗中枢神经系统中促甲状腺激素释放激素（TRH）的水平。在幼虫海七鳃鳗中，垂体复合体中约含609 pg TRH/mg，脑中含43.5±5.5 pg/mg（平均值±标准误），而脊髓中含11.2±2.3 pg/mg。成年海七鳃鳗和河七鳃鳗中的相应水平相似。完全脊髓横断并未显著改变损伤部位以下的TRH水平。因此，脊髓中所含的TRH独立于脊髓上轴突投射。