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立体定向机器人引导穿刺血肿引流与传统穿刺血肿引流治疗脑出血的临床疗效对比分析

Comparative analysis of clinical efficacy of stereotactic robot-guided puncture hematoma drainage and conventional puncture hematoma drainage in the treatment of intracerebral hemorrhage.

作者信息

Gong Xin, Dong Hai-Qing, Li Xin, Liu Zhen-Jie

机构信息

Xin Gong, Department of Neurosurgery, Baoding No.1 Central Hospital, Baoding, 071000, Hebei, China.

Hai-qing Dong, Department of Neurosurgery, Baoding No.1 Central Hospital, Baoding, 071000, Hebei, China.

出版信息

Pak J Med Sci. 2024 Sep;40(8):1675-1681. doi: 10.12669/pjms.40.8.8833.

Abstract

OBJECTIVE

To compare and analyze the clinical effectiveness of conventional puncture hematoma drainage and stereotactic robot-guided puncture hematoma drainage in managing intracerebral hemorrhage.

METHODS

This is clinical comparative research. One hundred and twenty patients with the intracerebral hemorrhage who underwent puncture hematoma drainage in Baoding No.1 Central Hospital from March 2020 to May 2023 were included and were assigned into the control groups(n=60) and experimental groups(n=60) according to different treatment methods. The experimental group underwent stereotactic robot-guided puncture hematoma drainage, while the control group underwent conventional puncture hematoma drainage treatment. The duration and situation of surgery, levels of inflammatory factors, as well as preoperative and 1-week postoperative GCS scores and NIHSS scores were compared and analyzed between the two groups.

RESULTS

In comparison with the control group, the experimental group exhibited considerably less surgical duration(p=0.00), higher amount of intraoperative blood drainage and hematoma clearance rate(p=0.00). The experimental group possessed a substantially more reduced incidence of complications(10%) in comparison with the control group(25%), with a statistically substantial distinction(p=0.03). After therapy, CRP, TNF-a, and IL-6 degrees were considerably more decreased (p=0.00) in the experimental group in comparison with the control group, while GCS grades were considerably more prominent and NIHSS grades were considerably more reduced (p=0.00).

CONCLUSION

Stereotactic robot-guided puncture hematoma drainage is a dependable and safe operative method to treat patients who had intracerebral hemorrhage, resulting in various benefits such as short length of operation, less injury, less inflammatory reaction, high hematoma clear efficiency and satisfactory recovery of neurological function.

摘要

目的

比较和分析传统穿刺血肿引流术与立体定向机器人引导穿刺血肿引流术治疗脑出血的临床疗效。

方法

本研究为临床对比研究。选取2020年3月至2023年5月在保定市第一中心医院接受穿刺血肿引流术的120例脑出血患者,根据不同治疗方法分为对照组(n = 60)和实验组(n = 60)。实验组采用立体定向机器人引导穿刺血肿引流术,对照组采用传统穿刺血肿引流术治疗。比较分析两组手术时间及情况、炎症因子水平、术前及术后1周的格拉斯哥昏迷量表(GCS)评分和美国国立卫生研究院卒中量表(NIHSS)评分。

结果

与对照组相比,实验组手术时间明显更短(p = 0.00),术中出血量更多,血肿清除率更高(p = 0.视情况补充具体数值0)。实验组并发症发生率(10%)明显低于对照组(25%),差异有统计学意义(p = 0.03)。治疗后,实验组的血清C反应蛋白(CRP)、肿瘤坏死因子-α(TNF-a)和白细胞介素-6(IL-6)水平明显低于对照组(p = 0.00),而GCS评分明显更高,NIHSS评分明显更低(p = 0.00)。

结论

立体定向机器人引导穿刺血肿引流术是治疗脑出血患者的一种可靠、安全的手术方法,具有手术时间短、损伤小、炎症反应轻、血肿清除效率高、神经功能恢复满意等优点。

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