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3D打印活性钛小梁椎间融合器在后路腰椎椎间融合术(PLIF)中的临床应用效果分析

An analysis of clinical application effects of 3d-printed act titanium trabecular intervertebral fusion cage in posterior lumbar interbody fusion (PLIF).

作者信息

Li Zhijun, Wang Hong, Wang Zhaoqi, Qi Zhiming, Yao Qi

机构信息

Zhijun Li, School of Graduates, Dalian Medical University, Dalian, 116044, Liaoning, China; Department of Orthopedics, The Second People's Hospital of Dalian, Dalian, 116011, Liaoning, China.

Hong Wang, Department of Orthopedics, Dalian Municipal Central Hospital Affiliated of Dalian Medical University, Dalian 116011, Liaoning, China.

出版信息

Pak J Med Sci. 2024 Sep;40(8):1791-1796. doi: 10.12669/pjms.40.8.8759.

Abstract

OBJECTIVE

To compare the clinical effects of applying a 3D-printed ACT titanium trabecular intervertebral fusion cage and a Polyetheretherketone (PEEK) cage in posterior lumbar interbody fusion (PLIF).

METHODS

This was a clinical comparative study. Forty patients with degenerative lumbar diseases admitted at The Second People's Hospital of Dalian from January 2020 to December 2021 were selected and divided into an observation group (3D cage) and a control group (PEEK cage) using the random number table method, with each group of 20 cases. The visual analogue scale (VAS) scores, Japanese Orthopaedic Association (JOA) scores, Cobb angles at fusion segments, intervertebral height and intervertebral fusion situations of the patients between the groups were compared.

RESULTS

No significant differences were found in their operation time, intraoperative blood losses and operation related complications(p>0.05). In terms of postoperative VAS and JOA scores in both groups, they are all significantly improved compared with those before the operation, and their differences are also statistically significant(0.05). However, no statistical significance exists in inter-group differences(p>0.05). Postoperative Cobb angles and intervertebral height of patients in both groups are considerably bettered compared with those before the operation. Their differences show statistical significance(0.05), while inter-group differences are proved to be not statistically significant(p>0.05).

CONCLUSIONS

Applying a 3D-printed ACT titanium trabecular intervertebral fusion cage or PEEK cage in PLIF has the potential to improve clinical symptoms of patients with degenerative lumbar diseases, and restore the Cobb angle and intervertebral height. 3D-printed ACT titanium trabecular intervertebral fusion cage can accelerate intervertebral fusion without increasing operation related complications.

摘要

目的

比较3D打印的ACT钛小梁椎间融合器与聚醚醚酮(PEEK)融合器在腰椎后路椎间融合术(PLIF)中的临床效果。

方法

这是一项临床对照研究。选取2020年1月至2021年12月在大连市第二人民医院收治的40例退变性腰椎疾病患者,采用随机数字表法分为观察组(3D融合器组)和对照组(PEEK融合器组),每组20例。比较两组患者的视觉模拟评分(VAS)、日本骨科学会(JOA)评分、融合节段的Cobb角、椎间高度及椎间融合情况。

结果

两组患者的手术时间、术中出血量及手术相关并发症比较,差异均无统计学意义(p>0.05)。两组患者术后VAS和JOA评分均较术前显著改善,差异有统计学意义(p<0.05),但组间差异无统计学意义(p>0.05)。两组患者术后Cobb角和椎间高度均较术前明显改善,差异有统计学意义(p<0.05),但组间差异无统计学意义(p>0.05)。

结论

在PLIF中应用3D打印的ACT钛小梁椎间融合器或PEEK融合器均有改善退变性腰椎疾病患者临床症状、恢复Cobb角和椎间高度的潜力。3D打印的ACT钛小梁椎间融合器可加速椎间融合,且不增加手术相关并发症。

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