伊拉克济加尔省18岁及以下血友病患者的患病率及临床人口统计学特征
Prevalence of Hemophilia and Clinicodemographic Characteristics of Hemophilic Patients Aged ≤ 18 Years in Thi-Qar, Iraq.
作者信息
Abood Ghada Mansoor, Dehiol Raid Kareem, Mones Hayfaa Mohammed
机构信息
University of Thi-Qar, Thi-Qar, Iraq.
Thi-Qar Health Directorate, Nasiriya, Thi-Qar, Iraq.
出版信息
Glob Pediatr Health. 2024 Sep 13;11:2333794X241280119. doi: 10.1177/2333794X241280119. eCollection 2024.
. This study aims to determine the prevalence of hemophilia in Thi-Qar, Iraq and study clinical and demographic characteristics of patients with hemophilia. . In this cross-sectional study, data were obtained by reviewing all patient medical records and interviewed with the patients and their parents in 2022. The total number of patients enrolled for this study was 110 children. . The prevalence of hemophilia in Thi-Qar was 9.5/100 000 population (18.7/100 000 males). Factor VIII inhibitors were positive in 13.1% of patients with hemophilia A (HA). Target joints were developed among 41.4% and 27.3% of patients with HA and hemophilia B, respectively. Hepatitis C virus was positive in 3% of those with HA. Inhibitors development and arthropathy were more among those with severe disease (22% and 46.3%, respectively). . Hemophilia prevalence in Thi-Qar was higher than the total prevalence in Iraq reported by World Federation of Hemophilia in 2022.
本研究旨在确定伊拉克济加尔省血友病的患病率，并研究血友病患者的临床和人口统计学特征。在这项横断面研究中，通过查阅2022年所有患者的病历并与患者及其父母进行访谈来获取数据。本研究纳入的患者总数为110名儿童。济加尔省血友病的患病率为9.5/10万人口（男性为18.7/10万）。13.1%的甲型血友病（HA）患者凝血因子VIII抑制物呈阳性。HA患者和乙型血友病患者中分别有41.4%和27.3%出现目标关节。3%的HA患者丙型肝炎病毒呈阳性。重度疾病患者中抑制物形成和关节病的发生率更高（分别为22%和46.3%）。济加尔省的血友病患病率高于世界血友病联盟2022年报告的伊拉克总患病率。
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