Tang Qingfeng, Chen Yan-Kun, Liu Shiping, Wang Jue, Zhang Liangliang, Qu Haoyu, An Hui
Digital and Intelligent Health Research Center, Anqing Normal University, Anqing 246133, China.
School of Traditional Chinese Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China.
Heliyon. 2024 Aug 28;10(17):e36785. doi: 10.1016/j.heliyon.2024.e36785. eCollection 2024 Sep 15.
This study extracts atherosclerosis indices from six channels of and discusses the data distribution, aims to explore the connection between cardiology of modern medicine (MM) and traditional Chinese medicine (TCM) pulse diagnosis.
We use a device capable of simultaneously collecting the pulse signals of the , and to test the population participating in routine physical examinations. Firstly, we collected pressure pulse waves from six channels of of 1045 healthy subjects (578 men and 467 women, average age=37.99±16.02 years). Secondly, we extracted the two most common arteriosclerosis indices pulse transit time (PTT) and Augmentation index (AIx) from six-channel pulse waves. Lastly, T-test and correlation test were taken to analyze the differences and relevance of the atherosclerosis indices extracted from six channels of .
When analyzing AIx and PTT at different wrist, it was found that AIx of left wrist is significantly higher than that of right wrist (<0.001), while the PTT of left wrist is significantly lower than that of right wrist (<0.001), a phenomenon that is common in both men and women. Furthermore, regardless of whether it is left or right wrist, the AIx at channel is higher than that at (<0.05) and (<0.05). At the same time, the PTT at is bigger than that at in two wrists (<0.05). However, when the specific channel is not considered, there is no significant difference in AIx and PTT between each channel and the corresponding wrist (>0.05). In addition, regardless of gender, when the specific channel is not considered, AIx and PTT of each wrist are significantly correlated with age (<0.001).
The differences of the atherosclerosis indices AIx and PTT in six channels support that the method of is indispensable in TCM. Additionally, the pulse waves obtained from each channel can be utilized as a dependable foundation for diagnosing atherosclerotic conditions. This study is beneficial for promoting the integration of TCM and MM in diagnosing disease.
本研究从六部脉中提取动脉粥样硬化指标并探讨其数据分布，旨在探索现代医学心脏病学与中医脉诊之间的联系。
我们使用一种能够同时采集寸、关、尺三部脉脉冲信号的设备对参加常规体检的人群进行检测。首先，采集了1045名健康受试者（578名男性和467名女性，平均年龄 = 37.99±16.02岁）的六部脉压力脉搏波。其次，从六部脉波中提取了两个最常见的动脉硬化指标脉搏传导时间（PTT）和增强指数（AIx）。最后，采用T检验和相关性检验分析六部脉提取的动脉粥样硬化指标的差异和相关性。
分析不同手腕处的AIx和PTT时发现，左手腕的AIx显著高于右手腕（<0.001），而左手腕的PTT显著低于右手腕（<0.001），这一现象在男性和女性中均普遍存在。此外，无论左手腕还是右手腕，寸部的AIx均高于关部（<0.05）和尺部（<0.05）。同时，两手腕处关部的PTT均大于寸部（<0.05）。然而，当不考虑具体通道时，各通道与相应手腕处的AIx和PTT无显著差异（>0.05）。此外，无论性别如何，当不考虑具体通道时，各手腕的AIx和PTT与年龄均显著相关（<0.001）。
六部脉中动脉粥样硬化指标AIx和PTT的差异支持了中医六部脉法的不可或缺性。此外，从各通道获得的脉搏波可作为诊断动脉粥样硬化状况的可靠依据。本研究有助于促进中医与现代医学在疾病诊断方面的融合。
