Demirel Esra, Cohen Seth, Ennis Ronald D, Nezhat Farr R
NYU Langone Hospital Long Island, Department of Minimally Invasive Gynecologic Surgery, Mineola, NY, United States.
Memorial Sloan Kettering Cancer Center, Department of Medicine, Gynecologic Medical Oncology, New York, NY, United States.
Gynecol Oncol Rep. 2024 Aug 22;55:101489. doi: 10.1016/j.gore.2024.101489. eCollection 2024 Oct.
Number of organ transplant recipients continues to rise worldwide with increasing accessibility and growing advancements in transplant medicine. Transplant patients have at least a two-to-four fold higher risk of developing cancer compared to the general population. As the prevalence of transplant patients increases, a growing number of these patients are expected to present with concurrent conditions such as cancer, requiring more complex and interdisciplinary care.
A 44-year-old patient with an intraperitoneal pelvic renal transplant, found to have high-grade ovarian adenocarcinoma most likely arising from endometriosis, successfully underwent surgical staging, adjuvant chemotherapy, and subsequent pelvic radiation for recurrence. Her kidney function and graft viability were preserved throughout her treatment with careful monitoring.
Management of reproductive tract cancers in kidney transplant recipients is complex. Current practices largely rely on evidence from observational studies and case reports for these cancers and more research is needed in this area.
随着移植医学的可及性提高和不断发展，全球器官移植受者的数量持续上升。与普通人群相比，移植患者患癌风险至少高出两到四倍。随着移植患者数量的增加，预计越来越多的此类患者会出现诸如癌症等并发疾病，需要更复杂的跨学科护理。
一名44岁接受腹腔盆腔肾移植的患者，被发现患有高级别卵巢腺癌，很可能源于子宫内膜异位症，成功接受了手术分期、辅助化疗以及后续针对复发的盆腔放疗。在整个治疗过程中，通过仔细监测，她的肾功能和移植肾的存活能力得以保留。
肾移植受者生殖道癌症的管理很复杂。目前的做法很大程度上依赖于针对这些癌症的观察性研究和病例报告所提供的证据，该领域还需要更多研究。
