Efared Boubacar, Boubacar Idrissa, Ousmane Kadre Kadre Alio, Abani Bako Aïchatou Balaraba, Boureima Habiba Salifou, Amadou Soumaila, Nouhou Hassan
Faculty of Health Sciences, Abdou Moumouni University, Niamey, Niger.
Pathology laboratory, Niamey National Hospital, Niamey, Niger.
Clin Pathol. 2024 Sep 12;17:2632010X241281460. doi: 10.1177/2632010X241281460. eCollection 2024 Jan-Dec.
Poroid neoplasms (PN) are a heterogeneous group of tumors deriving from sweat glands and folliculo-sebaceous units. Their histological classification and clinical features are challenging. Our aim was to report clinicopathological features of poroid neoplasms.
It is a retrospective study including all cases of poroid neoplasms registered at our Pathology laboratory of Niamey National Hospital (February 2020-February 2024).
We registered 13 cases of benign poroid neoplasms: 10 classic poromas (CP) (76.9%), 2 poroid hidradenomas (PH) (15.4%) and 1 dermal duct tumor (DDT) (7.7%). Nine cases (69.2%) had preoperative clinical diagnosis of malignancy. The mean age was 41.1 years (range of 12-70 years) with a slight female predominance. Only 4/13 cases (30.8%) had classical palmoplantar locations. The tumors mean size was 3.7 cm (range of 0.4-8 cm). Clear cells were present in 7 cases (53.8%), apocrine ductal differentiation (mixed or pure) in 6 cases (46.2%), keratin horns in 2 cases (15.4%), squamous eddies in 6 cases (46.2%), melanin pigments in 1 case (7.7%) and sebaceous differentiation in 2 cases (15.4%).
Unlike what is classically reported, our study shows that apocrine ductal differentiation, younger age and non-palmoplantar locations are common in poroid neoplasms.
类孔状肿瘤（PN）是一组起源于汗腺和毛囊皮脂腺单位的异质性肿瘤。其组织学分类和临床特征颇具挑战性。我们的目的是报告类孔状肿瘤的临床病理特征。
这是一项回顾性研究，纳入了尼亚美国家医院病理实验室登记的所有类孔状肿瘤病例（2020年2月至2024年2月）。
我们登记了13例良性类孔状肿瘤：10例经典汗孔瘤（CP）（76.9%），2例类孔状汗腺腺瘤（PH）（15.4%）和1例皮肤导管瘤（DDT）（7.7%）。9例（69.2%）术前临床诊断为恶性。平均年龄为41.1岁（范围12 - 70岁），女性略占优势。仅4/13例（30.8%）具有典型的掌跖部位。肿瘤平均大小为3.7厘米（范围0.4 - 8厘米）。7例（53.8%）存在透明细胞，6例（46.2%）有顶泌汗腺导管分化（混合或纯合），2例（15.4%）有角质角，6例（46.2%）有鳞状漩涡，1例（7.7%）有黑色素沉着，2例（15.4%）有皮脂腺分化。
与经典报道不同，我们的研究表明，顶泌汗腺导管分化、较年轻的年龄和非掌跖部位在类孔状肿瘤中较为常见。
