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与隆胸术后相关的结缔组织病和自身免疫性疾病:最新综述

Connective Tissue and Autoimmune Diseases Associated With Postsurgical Breast Augmentation: An Updated Review.

作者信息

Gichuru Timothy W, Raj Rhea, Gorantla Vasavi R

机构信息

School of Medicine, St. George's University School of Medicine, St. George's, GRD.

Medical Education, California University of Science and Medicine, Colton, USA.

出版信息

Cureus. 2024 Sep 12;16(9):e69275. doi: 10.7759/cureus.69275. eCollection 2024 Sep.

DOI:10.7759/cureus.69275
PMID:39282477
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11398728/
Abstract

This review provides an updated overview of the association between breast augmentation and connective tissue diseases (CTDs). A narrative review of recent literature was conducted. Various autoimmune disorders, such as Raynaud's syndrome, rheumatoid arthritis (RA), and Sjögren's syndrome, have been reported in association with breast implants, particularly silicone implants. Symptoms can be diverse and systemic, including fatigue, joint stiffness, muscle pain, skin rashes, and neurological and gastrointestinal issues. Explantation has shown promise in alleviating symptoms, but the exact pathogenesis remains unclear. Recent studies emphasize the need for informed consent, vigilant monitoring, and multidisciplinary management. The association between breast implants and CTDs remains contentious. While advancements in implant technology have improved patient outcomes, concerns about long-term health implications persist. Continuous research is necessary to elucidate the mechanisms underlying these potential risks and to develop informed patient care guidelines. In this narrative review, we discuss the history of breast implants, illness associated with breast augmentation, and treatment of CTDs and autoimmune diseases associated with breast augmentation.

摘要

本综述提供了隆胸与结缔组织病(CTD)之间关联的最新概述。对近期文献进行了叙述性综述。各种自身免疫性疾病,如雷诺氏综合征、类风湿性关节炎(RA)和干燥综合征,已被报道与乳房植入物有关,尤其是硅胶植入物。症状可能多种多样且具有全身性,包括疲劳、关节僵硬、肌肉疼痛、皮疹以及神经和胃肠道问题。取出植入物已显示出缓解症状的前景,但确切的发病机制仍不清楚。近期研究强调了知情同意、密切监测和多学科管理的必要性。乳房植入物与CTD之间的关联仍存在争议。虽然植入技术的进步改善了患者的治疗效果,但对长期健康影响的担忧依然存在。持续的研究对于阐明这些潜在风险的潜在机制以及制定明智的患者护理指南是必要的。在本叙述性综述中,我们讨论了乳房植入物的历史、与隆胸相关的疾病以及与隆胸相关的CTD和自身免疫性疾病的治疗。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1356/11398728/254020163076/cureus-0016-00000069275-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1356/11398728/9f96f8fbac1a/cureus-0016-00000069275-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1356/11398728/254020163076/cureus-0016-00000069275-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1356/11398728/9f96f8fbac1a/cureus-0016-00000069275-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1356/11398728/254020163076/cureus-0016-00000069275-i02.jpg

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本文引用的文献

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Silicone prosthetics and anti-thyroid autoimmunity.硅胶假体与抗甲状腺自身免疫性
Langenbecks Arch Surg. 2023 Aug 15;408(1):312. doi: 10.1007/s00423-023-03030-z.
2
Breast Implant-Associated Immunological Disorders.乳房植入物相关免疫性疾病。
J Immunol Res. 2022 May 4;2022:8536149. doi: 10.1155/2022/8536149. eCollection 2022.
3
History of breast implants: Back to the future.乳房植入物的历史:回到未来。
JPRAS Open. 2022 Mar 11;32:166-177. doi: 10.1016/j.jpra.2022.02.004. eCollection 2022 Jun.
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Raynaud's Phenomenon: Reviewing the Pathophysiology and Management Strategies.雷诺现象:病理生理学与管理策略综述
Cureus. 2022 Jan 28;14(1):e21681. doi: 10.7759/cureus.21681. eCollection 2022 Jan.
5
Effects of Silicone Breast Implants on Human Cell Types In Vitro: A Closer Look on Host and Implant.硅酮乳房植入物对体外人类细胞类型的影响:宿主和植入物的更深入观察。
Aesthetic Plast Surg. 2022 Oct;46(5):2208-2217. doi: 10.1007/s00266-021-02762-x. Epub 2022 Jan 24.
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Breast implant illness: scientific evidence of its existence.乳房植入病:其存在的科学证据。
Expert Rev Clin Immunol. 2022 Jan;18(1):15-29. doi: 10.1080/1744666X.2022.2010546. Epub 2022 Jan 5.
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A Practical Guide to Managing Patients With Systemic Symptoms and Breast Implants.系统性症状与乳房植入物患者管理实用指南
Aesthet Surg J. 2022 Mar 15;42(4):397-407. doi: 10.1093/asj/sjab375.
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Breast implant illness: a topic in review.乳房植入物疾病:综述主题
Gland Surg. 2021 Jan;10(1):430-443. doi: 10.21037/gs-20-231.
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The Evolution of Breast Implants.乳房植入物的演变
Semin Plast Surg. 2019 Nov;33(4):217-223. doi: 10.1055/s-0039-1696985. Epub 2019 Oct 17.
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Silicone breast implants and the risk of autoimmune/rheumatic disorders: a real-world analysis.硅树脂乳房植入物与自身免疫/风湿性疾病风险:真实世界分析。
Int J Epidemiol. 2018 Dec 1;47(6):1846-1854. doi: 10.1093/ije/dyy217.