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老年阿尔茨海默病患者和非阿尔茨海默病患者的口腔健康相关生活质量(OHRQoL)-评估研究。

Oral Health-Related Quality of Life (OHRQoL) in Elderly Patients with and without Alzheimer's Disease - An Evaluative Study.

机构信息

Department of Public Health Dentistry, College of Dental Science and Hospital, Indore, Madhya Pradesh, India.

Department of Public Health Dentistry, D.J. College of Dental Sciences and Research, Modinagar, Uttar Pradesh, India.

出版信息

Indian J Dent Res. 2024 Apr 1;35(2):149-153. doi: 10.4103/ijdr.ijdr_792_21. Epub 2024 Sep 14.

Abstract

BACKGROUND

Alzheimer's disease (AD) is a progressive neurodegenerative disorder characterised by the loss of intellectual functions. The disorder is usually seen after the age of 60 years, and these elderly patients tend to experience a progressive decline in their cognitive and behavioural abilities.

AIM

The present study was carried out to assess the oral health-related quality of life (OHRQoL) in elderly patients suffering from AD as compared to subjects without the disease.

MATERIALS AND METHOD

One hundred elderly subjects with AD and 150 subjects without AD were included in the study. The subjective assessment of OHRQoL was done using the General Oral Health Assessment Index (GOHAI). Demographic and oral characteristics were assessed for dentition status with the Decayed, Missing and Filled Teeth (DMFT) index, Oral Hygiene Index (OHI), prosthesis use, xerostomia and presence of oral pathologies.

RESULTS

GOHAI values were found to be statistically higher ( P = 0.0003) in the subjects with AD. The subjects with AD were found to have a higher DMFT (mean difference = 4.11), Oral Hygiene Index (OHI) scores (mean difference = 1.54), xerostomia ( P = 0.0128) and number of oral pathologies. However, the educational level ( P = 0.2603) and number of natural teeth ( P = 0.0006) were found to be lower in the group with AD.

CONCLUSION

The present study reported that the elderly subjects suffering from AD had poorer OHRQoL than those without the disease. There is a need to comprehensively evaluate the oral health conditions of elderly patients with AD and actively provide management to improve their OHRQoL.

摘要

背景

阿尔茨海默病(AD)是一种进行性神经退行性疾病,其特征是智力功能丧失。这种疾病通常发生在 60 岁以后,这些老年患者往往会经历认知和行为能力的逐渐下降。

目的

本研究旨在评估患有 AD 的老年患者与无该病的患者相比,其口腔健康相关生活质量(OHRQoL)。

材料和方法

本研究纳入了 100 名患有 AD 的老年患者和 150 名无 AD 的患者。使用一般口腔健康评估指数(GOHAI)对 OHRQoL 进行主观评估。评估牙列状况的人口统计学和口腔特征包括龋齿、缺失和补牙(DMFT)指数、口腔卫生指数(OHI)、义齿使用、口干和口腔疾病的存在。

结果

AD 患者的 GOHAI 值明显更高(P=0.0003)。AD 患者的 DMFT(平均差异=4.11)、口腔卫生指数(OHI)评分(平均差异=1.54)、口干(P=0.0128)和口腔疾病数量更高。然而,AD 组的受教育程度(P=0.2603)和天然牙数量(P=0.0006)较低。

结论

本研究报告称,患有 AD 的老年患者的 OHRQoL 比无该病的患者差。需要全面评估患有 AD 的老年患者的口腔健康状况,并积极提供管理以改善他们的 OHRQoL。

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