Department of Women's and Children's Health, University of Padua.
Reumatismo. 2024 Sep 11;76(3). doi: 10.4081/reumatismo.2024.1778.
The knowledge of ankylosing spondylitis is rising, and more and more attention is being paid to the diagnosis of this pathology in females. The purpose of this narrative review is to emphasize the role of reproductive health in women with ankylosing spondylitis, with particular attention to contraception and fertility.
A comprehensive review of the literature was performed to evaluate the reproductive health of women with ankylosing spondylitis.
Oral contraception has been shown to be safe in women with ankylosing spondylitis, with no contraceptive benefits that should be evaluated during counseling. In the literature, there is no strong data regarding fertility in women with ankylosing spondylitis. It seems that these women may have impaired fertility due to reduced ovarian reserve, pharmacological treatments, and reduced sexual activity due to the concern that offspring may contract the disease. A multidisciplinary approach is needed in these women to ensure an adequate evaluation of sexual activity as an important aspect of quality of life and to counsel regarding family planning to address patients' concerns on contraception, fertility desire, and fertility preservation.
Lifestyle factors should be investigated to improve fertility and disease activity without medications. Further trials are needed to investigate the reproductive health of women with ankylosing spondylitis.
强直性脊柱炎的相关知识不断普及，人们越来越关注女性患者的这种病理诊断。本综述旨在强调生殖健康在女性强直性脊柱炎患者中的重要性，特别关注避孕和生育问题。
全面检索相关文献，评估强直性脊柱炎女性患者的生殖健康状况。
口服避孕药在强直性脊柱炎女性中是安全的，在咨询过程中不应评估其避孕效果。文献中关于强直性脊柱炎女性生育力的数据并不充分。这些女性的生育力可能受损，原因包括卵巢储备减少、药物治疗以及因担心子女患病而减少了性行为。因此，需要对这些女性采取多学科方法，确保对性生活这一重要生活质量方面进行充分评估，并提供有关避孕、生育愿望和生育力保存的咨询，以解决患者的相关顾虑。
应调查生活方式因素，在不使用药物的情况下改善生育力和疾病活动度。需要进一步的试验来研究强直性脊柱炎女性的生殖健康。
