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超声引导下微创置管联合黄柏液治疗哺乳期乳腺脓肿的临床研究

Clinical study of ultrasound-guided minimally invasive catheterization combined with compound cortex phellodendri fluid in the treatment of lactational breast abscess.

作者信息

Wang Na, Gong Lili, Ye Chunmei

机构信息

Department of Breast, Wuhan Children's Hospital (Wuhan Maternal and Child Healthcare Hospital), Tongji Medical College, Huazhong University of Science & Technology, Wuhan, China.

出版信息

PLoS One. 2024 Sep 16;19(9):e0308548. doi: 10.1371/journal.pone.0308548. eCollection 2024.

DOI:10.1371/journal.pone.0308548
PMID:39283924
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11404787/
Abstract

OBJECTIVE

To retrospectively analyze the clinical practicability and value of ultrasound-guided minimally invasive catheterization combined with compound Phellodendron Phellodendri liquid in the treatment of breast abscess during lactation.

METHODS

139 patients with lactational breast abscess discharged from our hospital from January 2021 to November 2023 were selected. We divided them into groups according to treatment methods, analyzed whether there were statistical differences in observation indexes among groups and the risk factors affecting breastfeeding rate and treatment satisfaction.

RESULTS

We found that numerical rating scale(NRS) score and incidence of breast fistula in group A were significantly lower than other, the continuous decrease of postoperative drainage in group A was higher than other, there were significant differences among groups (p<0.001). Univariate analysis showed that recovery time, drainage tube placement time, postoperative redness and swelling regression time, scar length, and VAS score of six groups were statistically significant (p<0.001). We found that the overall satisfaction and the rate of continued breastfeeding in group A (96.2%) were higher than other, the differences were statistically significant(p<0.05). Logistic regression analysis revealed that the significant risk factors influencing treatment satisfaction included the time of drainage tube placement, postoperative redness and swelling regression time, treatment group, surgical method, NRS score on the first day after operation, postoperative drainage volume, healing time, scar length, flushing drugs, and VAS score. Postoperative redness and swelling regression time, treatment group, operation method and VAS score are all risk factors that influence the outcome of breastfeeding.

CONCLUSION

Ultrasound-guided minimally invasive catheterization combined with compound cortex phellodendri fluid in the treatment of breast abscess during lactation can not only reduce the pain caused by dressing change, but also offer numerous advantages, including shorter healing time, beautiful appearance, lower incidence of breast fistula, high satisfaction and high rate of continued breastfeeding.

摘要

目的

回顾性分析超声引导下微创置管联合复方黄柏液治疗哺乳期乳腺脓肿的临床实用性及价值。

方法

选取2021年1月至2023年11月在我院出院的139例哺乳期乳腺脓肿患者。根据治疗方法分组,分析各组观察指标是否存在统计学差异以及影响母乳喂养率和治疗满意度的危险因素。

结果

发现A组数字评分量表(NRS)评分及乳腺瘘发生率显著低于其他组,A组术后引流量持续减少幅度高于其他组,组间差异有统计学意义(p<0.001)。单因素分析显示,六组的恢复时间、引流管放置时间、术后红肿消退时间、瘢痕长度及视觉模拟评分(VAS)均有统计学意义(p<0.001)。发现A组总体满意度及继续母乳喂养率(96.2%)高于其他组,差异有统计学意义(p<0.05)。Logistic回归分析显示,影响治疗满意度的显著危险因素包括引流管放置时间、术后红肿消退时间、治疗组、手术方式、术后第1天NRS评分、术后引流量、愈合时间、瘢痕长度、冲洗药物及VAS评分。术后红肿消退时间、治疗组、手术方式及VAS评分均是影响母乳喂养结局的危险因素。

结论

超声引导下微创置管联合复方黄柏液治疗哺乳期乳腺脓肿,不仅可减轻换药所致疼痛,还具有愈合时间短、外形美观、乳腺瘘发生率低、满意度高及继续母乳喂养率高等诸多优点。

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